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FindNeighboringGenes - neigborhood bug?

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2009-09-21
2012-09-20
  • Deniz Koellhofer

    Hi

    I've been working with the FindNeighboringGenes tool and trying to limit the
    neighborhood with the -b option. However it seems that genes even far outside
    of this boundary are reported. Is that a bug in the software or am I using the
    -b option in a wrong way?

    So, far I've filtered the FNG file with the following awk command:

    awk 'FS="\t" { if($1 || ($4 && $4 <= 1000)) {print $0 }
    }' FNG.xls

    This removes all hits outside of the specified 1000bp boundary.

    Thanks,

    Deniz

     
  • Deniz Koellhofer

    Just wanted to show an example:

    Example output for "-b 1500" option

    chr10 374751 375342 0.0

    204404 73 NM_212479 chr10 170642 285200 + 170642 Closest

    204404 73 NM_006624 chr10 170642 290576 + 170642 Closest

    chr10 1300976 1301497 1.0

    105529 594 NR_015376 chr10 1195707 1200611 + 1195707 Closest

    chr10 2386896 2387760 2.0

    617611 74 NM_018702 chr10 1218072 1769717 - 1769717 Closest

    If I'm looking at the right columns, these genes seem to have greater
    distances than 1,500bp (e.g. 204,404bp).

     
  • Deniz Koellhofer

    Sorry, about the garbled message - here again:

    Example output for "-b 1500" option

    chr10 374751 375342 0.0

    204404 73 NM_212479 chr10 170642 285200 + 170642 Closest

    204404 73 NM_006624 chr10 170642 290576 + 170642 Closest

    chr10 1300976 1301497 1.0

    105529 594 NR_015376 chr10 1195707 1200611 + 1195707 Closest

    chr10 2386896 2387760 2.0

    617611 74 NM_018702 chr10 1218072 1769717 - 1769717 Closest

    If I'm looking at the right columns, these genes seem to have greater
    distances than 1,500bp (e.g. 204,404bp).

     

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