[Transdecoder-users] Announcement: TransDecoder v2.0
Extracting likely coding regions from transcript sequences
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bhaas
From: Brian H. <bh...@br...> - 2015-01-27 00:54:57
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Greetings all. A new and revised version of TransDecoder is now available. Note, we've moved the project to github, so please visit the new website: http://transdecoder.github.io and we have a new google group for user support and discussions at: https://groups.google.com/forum/#!forum/transdecoder-users This new version of TransDecoder has the following features: Blast homology (new) in addition to Pfam domain hits (earlier) can be used to ensure that protein-homologous regions are retained among the coding region predictions. The software now runs in two (or 3) distinct phases: 1. There's TransDecoder.LongOrfs that is used to identify all candidate ORFs. (1b) search these using blast or pfam searches 2. There's TransDecoder.Predict that does the final predictions, optionally using the search results from (1b) The new web documentation provides pointers for how to do the blast or pfam searches, as well as directing users to the new http://hpcgridrunner.github.io/ project to facilitate grid-level bioifx computes needed for this. Also, for those that are Trinotate ( http://trinotate.sf.net) users, the outputs from (1b) will be directly suitable for upload into Trinotate. The software build process is hugely simplified and the package itself has been trimmed down to include only the essentials (cd-hit). -- -- Brian J. Haas The Broad Institute http://broadinstitute.org/~bhaas <http://broad.mit.edu/~bhaas> |