Combinatorial therapies have been recently proposed for improving anticancer treatment efficacy. SynergyFinder R package is a software tool to analyze pre-clinical drug combination datasets developed in our group. To facilitate the use of the R package for the drug discovery community, we also provide a web server called SynergyFinder PLus at http://synergyfinder.org/ that provides a user-friendly interface to enable a more flexible and versatile analysis of drug combination data.
Sister websites:
https://tangsoftwarelab.shinyapps.io/synergyfinder/
Bioconductor R package:
https://www.bioconductor.org/packages/release/bioc/html/synergyfinder.html
Citation:
Zheng, S.; Wang, W.; Aldahdooh, J.; Malyutina, A.; Shadbahr, T.; Tanoli Z; Pessia, A.; Tang, J. SynergyFinder Plus: Toward Better Interpretation and Annotation of Drug Combination Screening Datasets. Genomics, Proteomics & Bioinformatics 2022, 20, 587-596 https://doi.org/10.1016/j.gpb.2022.01.004
Features
- Drug discovery
- FAIR sharing of open-source tools