[svtoolkit-help] CNV detection in pedigrees

[Homann, O. <oh...@am...>]

Hello,

I'm hoping to use STRiP for CNV detection in support of a sequencing project.   After looking over the documentation, I find myself unsure of whether it is appropriate for my dataset.  Specifically, I have ~100 samples covering 10 pedigrees, and wonder whether the inter-relatedness of some of the samples would impact SV modeling and detection.  Any guidance you can offer would be much appreciated.

Regards,
Oliver Homann