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References

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Johannes W. Dietrich

References

General Information on the Cybernetic Theory

  1. Dietrich JW. Signal Storage in Metabolic Pathways: The ASIA Element. kybernetiknet. 2000;1(3, 2000):1-9.

  2. Dietrich, J. W. and B. O. Boehm (2006). Equilibrium behaviour of feedback-coupled physiological saturation kinetics. In: Cybernetics and Systems 2006. R. Trappl (Hrsg). Vienna, Austrian Society for Cybernetic Studies. 1: 269-74.

  3. Dietrich JW: A Methodology for Vertical Translation Between Molecular and Organismal Level in Biological Feedback Loops. .bioRxiv; 2021. doi: 10.1101/2021.09.20.461028.

  4. Dietrich JW, Siegmar N, Hojjati JR, Gardt O, Boehm BO: CyberUnits Bricks: An Implementation Study of a Class Library for Simulating Nonlinear Biological Feedback Loops. ADCAIJ: Advances in Distributed Computing and Artificial Intelligence Journal 2024, 13. doi: 10.14201/adcaij.31762.

SPINA Carb

  1. Dietrich JW, Dasgupta R, Anoop S, Jebasingh F, Kurian ME, Inbakumari M, Boehm BO, Thomas N. SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function. Sci Rep. 2022 Oct 21;12(1):17659. doi: 10.1038/s41598-022-22531-3. PMID: 36271244; PMCID: PMC9587026.

  2. Dietrich JW, Abood A, Dasgupta R, Anoop S, Jebasingh FK, Spurgeon R, Thomas N, Boehm BO. A novel simple disposition index (SPINA-DI) from fasting insulin and glucose concentration as a robust measure of carbohydrate homeostasis. J Diabetes. 2024 Sep;16(9):e13525. doi: 10.1111/1753-0407.13525. Epub 2024 Jan 2. PMID: 38169110; PMCID: PMC11418405.

  3. Bansal V, Winkelmann BR, Dietrich JW, Boehm BO. Whole-exome sequencing in familial type 2 diabetes identifies an atypical missense variant in the RyR2 gene. Front Endocrinol (Lausanne). 2024 Feb 20;15:1258982. doi: 10.3389/fendo.2024.1258982. PMID: 38444585; PMCID: PMC10913019.

  4. Dietrich JW: P4-Endokrinologie – Kybernetische Perspektiven eines neuen Ansatzes. Leibniz Online 2024, 54. doi: 10.53201/LEIBNIZONLINE54.

  5. Abu Rached N, Dietrich JW, Ocker L, Stockfleth E, Haven Y, Myszkowski D, Bechara FG. Endotyping Insulin-Glucose Homeostasis in Hidradenitis Suppurativa: The Impact of Diabetes Mellitus and Inflammation. J Clin Med. 2025 Mar 21;14(7):2145. doi: 10.3390/jcm14072145. PMID: 40217596; PMCID: PMC11990022.

SPINA Thyr

  1. Dietrich JW, Mitzdorf U, Weitkunat R, Pickardt CR. The pituitary-thyroid feedback control: stability and oscillations in a new nonlinear model. Journal of Endocrinological Investigation. 1997;20(Suppl. to no. 5):100.

  2. Dietrich JW, Fischer MR, Jauch J, Pantke E, Gärtner R, Pickardt CR. SPINA-THYR: A novel systems theoretic approach to determine the secretion capacity of the thyroid gland. European Journal of Internal Medicine. 1999;10 (Suppl. 1)(May 1999):S34.

  3. Dietrich JW, Tesche A, Pickardt CR, Mitzdorf U. Fractal Properties of the Thyrotropic Feedback Control: Implications of a Nonlinear Model Compared with Empirical Data. In: Trappl R, ed. Cybernetics and Systems 2002. Vienna: Austrian Society for Cybernetic Studies; 2002:329-34.

  4. Dietrich JW. Der Hypophysen-Schilddrüsen-Regelkreis. Entwicklung und klinische Anwendung eines nichtlinearen Modells. Vol. 2 Berlin: Logos-Verlag; 2002. (Schardt F, ed. Spektrum medizinischer Forschung).

  5. Dietrich JW, Tesche A, Pickardt CR, Mitzdorf U. Thyrotropic Feedback Control: Evidence for an Additional Ultrashort Feedback Loop from Fractal Analysis. Cybernetics and Systems. 2004;35(4):315-31. doi: 10.1080/01969720490443354

  6. Dietrich, J. W., A. Stachon, B. Antic, H. H. Klein und S. Hering (2008). The AQUA-FONTIS Study: Protocol of a multidisciplinary, cross-sectional and prospective longitudinal study for developing standardized diagnostics and classification of non-thyroidal illness syndrome. BMC Endocrine Disorders 8 (13). PMID 18851740, doi 10.1186/1472-6823-8-13

  7. Dietrich, J. W., G. Landgrafe, E. H. Fotiadou (2012). TSH and thyrotropic agonists: Key actors in thyroid homeostasis. Journal of Thyroid Research, vol. 2012, Article ID 351864, 29 pages, 2012. PMID 23365787, doi:10.1155/2012/351864.

  8. Hoermann, R., J. E. M. Midgley, R. Larisch, J. W. Dietrich (2013). Is Pituitary Thyrotropin an Adequate Measure Of Thyroid Hormone-Controlled Homeostasis During Thyroxine Treatment?. European Journal of Endocrinology 168(2):271-80. PMID 23184912, doi: 10.1530/EJE-12-0819

  9. Midgley, J. E. M., R. Hoermann, R. Larisch, J. W. Dietrich (2013). Physiological states and functional relation between thyrotropin and free thyroxine in thyroid health and disease: in vivo and in silico data suggest a hierarchical model. Journal of Clinical Pathology 66(4):335-42. PMID 23423518, doi: 10.1136/jclinpath-2012-201213

  10. Hoermann R, Midgley JE, Giacobino A, Eckl WA, Wahl HG, Dietrich JW, Larisch R. (2014) Homeostatic Equilibria Between Free Thyroid Hormones and Pituitary Thyrotropin Are Modulated By Various Influences Including Age, Body Mass Index and Treatment. Clin Endocrinol (Oxf). 81(6):907-15. doi: 10.1111/cen.12527. PMID 24953754.

  11. Hoermann R, Midgley JE, Larisch R, Dietrich JW (2015). Integration of Peripheral and Glandular Regulation of Triiodothyronine Production by Thyrotropin in Untreated and Thyroxine-Treated Subjects. Hormone and Metabolic Research, PMID: 25750078 doi: 10.1055/s-0034-1398616.

  12. Dietrich JW, Müller M, Schiedat F, Schlömicher M, Strauch J, Chatzitomaris A, Klein HH, Mügge A,Köhrle J,Rijntjes, E, Lehmphul, I (2015). NTIS in cardiac illness involves elevated concentrations of 3,5-T2 and correlates to atrial remodelling. European thyroid journal. 2015; 4(2):129-37. PMID: 26279999 doi: 10.1159/000381543.

  13. Dietrich JW, Landgrafe-Mende G, Wiora E, Chatzitomaris A, Klein HH., Midgley JE, Hoermann R (2016). Calculated parameters of thyroid homeostasis: Emerging tools for differential diagnosis and clinical research. Frontiers in Endocrinology. 2016; 7:00057. PMID:27375554 doi: 10.3389/fendo.2016.00057.

  14. Hoermann R, Midgley JE, Larisch R, Dietrich JW (2016). Relational Stability of Thyroid Hormones in Euthyroid Subjects and Patients with Autoimmune Thyroid Disease. Eur Thyroid J. 2016 Sep;5(3):171-179. PMID 27843807. doi 10.1159/000447967

  15. Chatzitomaris A, Hoermann R, Midley JE, Hering S, Urban A, Dietrich B, Abood A, Klein HH, Dietrich JW (2017). Thyroid Allostasis – Adaptive Responses of Thyrotropic Feedback Control to Conditions of Strain, Stress and Developmental Programming. Frontiers in Endocrinology. 2017; 8:00163. doi: 10.3389/fendo.2017.00163

  16. Hoermann R, Midgley JEM, Larisch R, Dietrich JWC. Advances in applied homeostatic modelling of the relationship between thyrotropin and free thyroxine. PLoS One. 2017 Nov 20;12(11):e0187232. doi 10.1371/journal.pone.0187232. PMID 29155897.

  17. Hoermann R, Midgley JEM, Larisch R, Dietrich JW. The Role of Functional Thyroid Capacity in Pituitary Thyroid Feedback Regulation. Eur J Clin Invest. 2018 Jul 19:e13003. doi: 10.1111/eci.13003. PMID 30022470.

  18. Aweimer A, El-Battrawy I, Akin I, Borggrefe M, Mügge A, Patsalis PC, Urban A, Kummer M, Vasileva S, Stachon A, Hering S, Dietrich JW. Abnormal thyroid function is common in takotsubo syndrome and depends on two distinct mechanisms: results of a multicentre observational study. J Intern Med. 2021 May;289(5):675-687. doi: 10.1111/joim.13189. Epub 2020 Nov 12. PMID 33179374.

  19. Aweimer A, Schiedat F, Schöne D, Landgrafe-Mende G, Bogossian H, Mügge A, Patsalis PC, Gotzmann M, Akin I, El-Battrawy I, Dietrich JW. Abnormal Cardiac Repolarization in Thyroid Diseases: Results of an Observational Study. Front Cardiovasc Med. 2021 Nov 23;8:738517. doi: 10.3389/fcvm.2021.738517. PMID: 34888359; PMCID: PMC8649843.

  20. Abu Rached N, Dietrich JW, Ocker L, Quast DR, Scheel C, Gambichler T, Bechara FG. Primary Thyroid Dysfunction Is Prevalent in Hidradenitis Suppurativa and Marked by a Signature of Hypothyroid Graves' Disease: A Case-Control Study. J Clin Med. 2023 Dec 4;12(23):7490. doi: 10.3390/jcm12237490. PMID: 38068542; PMCID: PMC10707714.

  21. Aweimer A, Dietrich JW, Santoro F, Fàbregas MC, Mügge A, Núñez-Gil IJ, Vazirani R, Vedia O, Pätz T, Ragnatela I, Arcari L, Volpe M, Corbì-Pascual M, Martinez-Selles M, Almendro-Delia M, Sionis A, Uribarri A, Thiele H, Brunetti ND, Eitel I, Stiermaier T, Hamdani N, Abumayyaleh M, Akin I, El-Battrawy I. Takotsubo syndrome outcomes predicted by thyroid hormone signature: insights from cluster analysis of a multicentre registry. EBioMedicine. 2024 Apr;102:105063. doi: 10.1016/j.ebiom.2024.105063. Epub 2024 Mar 18. PMID: 38502972; PMCID: PMC10963195.

  22. Bazika-Gerasch B, Kumowski N, Enax-Krumova E, Kaisler M, Eitner LB, Maier C, Dietrich JW. Impaired autonomic function and somatosensory disturbance in patients with treated autoimmune thyroiditis. Sci Rep. 2024 May 29;14(1):12358. doi: 10.1038/s41598-024-63158-w. PMID: 38811750; PMCID: PMC11137073.

  23. Dietrich JW: P4-Endokrinologie – Kybernetische Perspektiven eines neuen Ansatzes. Leibniz Online 2024, 54. doi: 10.53201/LEIBNIZONLINE54.

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