#435 Indels at protein level

[Pascale Gaudet]

Hi,

I'd like to have terms to represent indels at the protein level (or please indicate what we should be using).
Right now at the transcript level there are:
-- conservative_inframe_insertion
-- disruptive_inframe_insertion
-- conservative_inframe_deletion
-- disruptive_inframe_deletion

The "conservative" terms do have corresponding polypeptides effects: amino_acid_insertion and amino_acid_deletion

But there are no polypeptide effects that correspond to the 'disruptive' versions.
There needs to be indel and frameshifts. Also, if you want a correspondence between the transcript effect and the effect on the polypeptide, you may want to describe 'indel with gain of amino acids' and 'indel with loss of amino acids' (I am not sure what the best formulation may be !)

Thanks,

Pascale

[Chris Mungall]

Hi Pascale - just like GO, SO has moved its tracker, now here: https://github.com/The-Sequence-Ontology/SO-Ontologies/issues