#405 NTR: cis-acting homologous chromosome pairing factor

[Valerie Wood]

term: cis-acting homologous chromosome pairing factor

proposed def: A genome region where chromosome pairing occurs preferentially during homologous chromosome pairing during early meiotic prophase of Meiosis I.

comment: An example of this is the Sme2 locus in fission yeast S. pombe, where is is coincident with an ribonuclear complex termed the "Mei2 dot"
refs: PMID:22582262, PMID:24173580, PMID:23117617

synonym related: "sme2 locus" (so far this is the only know example in eukaryotedom so I think it could be a synonym, it is not known if there are others in pombe)

[Valerie Wood]

change "factor" to "region"

[Karen Eilbeck]

This is a little confusing to me as it looks like Sme2 is transcribed. Is it a kind of transcript or a DNA motif?

(Also sorry for not getting back to you sooner.)
--K

[Valerie Wood]

Hi Karen,

It's both. It is a transcribed region, but the DNA locus is important to initiate chromosome pairing (by some mechanism which involves the non-coding transcript). We want to define a term in our phenotype ontology which refers specifically to the DNA locus, and not the RNA, as this is functionally significant, independently of the transcript.

This is the main paper PMID:22582262

Cheers,

val

[Valerie Wood]

Hi Karen,
Is this request OK? (I don't see the term yet)
cheers
val

On 31/05/2014 08:56, Valerie Wood wrote:

Hi Karen,

It's both. It is a transcribed region, but the DNA locus is important
to initiate chromosome pairing (by some mechanism which involves the
non-coding transcript). We want to define a term in our phenotype
ontology which refers specifically to the DNA locus, and not the RNA,
as this is functionally significant, independently of the transcript.

This is the main paper PMID:22582262

Cheers,

val

---

[term-tracker:#405] http://sourceforge.net/p/song/term-tracker/405/
NTR: cis-acting homologous chromosome pairing factor

Status: open
Group:
Created: Tue Jan 28, 2014 01:45 PM UTC by Valerie Wood
Last Updated: Fri May 30, 2014 08:53 PM UTC
Owner: nobody

term: cis-acting homologous chromosome pairing factor

proposed def: A genome region where chromosome pairing occurs
preferentially during homologous chromosome pairing during early
meiotic prophase of Meiosis I.

comment: An example of this is the Sme2 locus in fission yeast S.
pombe, where is is coincident with an ribonuclear complex termed the
"Mei2 dot"
refs: PMID:22582262, PMID:24173580, PMID:23117617

synonym related: "sme2 locus" (so far this is the only know example in
eukaryotedom so I think it could be a synonym, it is not known if
there are others in pombe)

---

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[Karen Eilbeck]

I'll have a look today
--K

On Jun 26, 2014, at 2:18 PM, Valerie Wood wrote:

Hi Karen,
Is this request OK? (I don't see the term yet)
cheers
val

On 31/05/2014 08:56, Valerie Wood wrote:

Hi Karen,

It's both. It is a transcribed region, but the DNA locus is important
to initiate chromosome pairing (by some mechanism which involves the
non-coding transcript). We want to define a term in our phenotype
ontology which refers specifically to the DNA locus, and not the RNA,
as this is functionally significant, independently of the transcript.

This is the main paper PMID:22582262

Cheers,

val

---

[term-tracker:#405]http://sourceforge.net/p/song/term-tracker/405/ http://sourceforge.net/p/song/term-tracker/405/
NTR: cis-acting homologous chromosome pairing factor

Status: open
Group:
Created: Tue Jan 28, 2014 01:45 PM UTC by Valerie Wood
Last Updated: Fri May 30, 2014 08:53 PM UTC
Owner: nobody

term: cis-acting homologous chromosome pairing factor

proposed def: A genome region where chromosome pairing occurs
preferentially during homologous chromosome pairing during early
meiotic prophase of Meiosis I.

comment: An example of this is the Sme2 locus in fission yeast S.
pombe, where is is coincident with an ribonuclear complex termed the
"Mei2 dot"
refs: PMID:22582262, PMID:24173580, PMID:23117617

synonym related: "sme2 locus" (so far this is the only know example in
eukaryotedom so I think it could be a synonym, it is not known if
there are others in pombe)

---

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---

[term-tracker:#405]http://sourceforge.net/p/song/term-tracker/405/ NTR: cis-acting homologous chromosome pairing factor

Status: open
Group:
Created: Tue Jan 28, 2014 01:45 PM UTC by Valerie Wood
Last Updated: Sat May 31, 2014 07:56 AM UTC
Owner: nobody

term: cis-acting homologous chromosome pairing factor

proposed def: A genome region where chromosome pairing occurs preferentially during homologous chromosome pairing during early meiotic prophase of Meiosis I.

comment: An example of this is the Sme2 locus in fission yeast S. pombe, where is is coincident with an ribonuclear complex termed the "Mei2 dot"
refs: PMID:22582262, PMID:24173580, PMID:23117617

synonym related: "sme2 locus" (so far this is the only know example in eukaryotedom so I think it could be a synonym, it is not known if there are others in pombe)

---

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Karen Eilbeck
Associate Professor
Department of Biomedical Informatics, University of Utah

[Karen Eilbeck]

SO:0002025 done