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SoloDel (Somatic Low-frequent Deletion call model) is a Java based somatic deletion caller designed for whole-genome sequencing data from unmatched samples. SoloDel is specialized for identifying somatic deletions with frequently existing sampling issues : low mutational frequency in cell population and absence of the matched control samples.
The important features of SoloDel are:
• Estimation of mutational frequency in a mixed disease sample without matched control
• Improved somatic deletion calling based on the probabilistic model with the parameter estimation
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