SimulaBeta Activity
A simulation program for insulin-glucose homeostasis.
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jwdietrich
Activity for SimulaBeta
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Johannes W. Dietrich committed [r178] on Code
Adjusting compiler options to enable linking on macOS Tahoe 26.
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Updating CyberUnits Bricks library.
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Updating CyberUnits Bricks library.
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Correcting naming conventions; Several updates.
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Minor fixes and optimisations.
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Updating README.md
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Creating test scenarios.
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Adding option to save the duration of a simulation run in scenario files and fixing several bugs.
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Fixing reference.
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SimulaBeta released /Documentation/SimulaBeta_Technical_Reference_C_V_3_1.pdf
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SimulaBeta paves the way for improved diagnostical strategies in diabetes care and clinical research. Early diagnosis of diabetes mellitus continues to be a challenge. Established test protocols are either elaborate and expensive or of limited quality, and even the concept of prediabetes is debated. The key determinants of glucose homeostasis, beta cell function and insulin sensitivity, have low utility when assessed independently. Their combination, the dynamic disposition index, a measure of the...
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Combined with mathematical modelling, based on SimulaBeta, a single blood sample may be better than a complex test
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Additional steps for implementing the reading of LOREMOS sequences from scenario XML files.
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Additional steps for loading of LOREMOS sequences from scenario XML files implemented.
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SimulaBeta crashes if windows are closed
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SimulaBeta crashes if windows are closed
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This issue has been partly addressed in commit r162. Further investigations on the reason for the crash are ungoing.
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Implementing loading of LOREMOS sequences from scenario XML files.
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Extending handling of LOREMOS sequences in scenario handler.
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First step for integration of LOREMOS sequences in saved scenarios.
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Extending one-way sensitivity analysis.
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Implementing a first prototypical version of one-way sensitivity analysis.
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SimulaBeta crashes if windows are closed
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Integration of a Window menu and adaptations of code to be compatible with Lazarus 3.0.
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SimulaBeta crashes if windows are closed
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Minor updates.
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SimulaBeta crashes if windows are closes
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Version History
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Version History
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SimulaBeta 3.1.2 available
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Version 3.1.2 is available, fixing several bugs and being based on CyberUnits 2.0.
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Tagging SimulaBeta 3.1.2
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Final steps for SimulaBeta 3.1.2
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Updating foundation classes to CyberUnits Bricks 2.0.
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Correcting version identifier.
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Fixing a bug in the reset function of Simulation Control.
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Fixing a bug that affected the generation of XML files for scenarios.
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Memory leaks
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Fixed in SimulaBeta 3.1.1 (commits r146 to r154).
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Misaligned colour marks
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Fixed in SimulaBeta 3.1.1 (commits r146 to r154).
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Memory leaks
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Memory leaks
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Memory leaks
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SimulaBeta has been updated to version 3.1.1. This bug-fix release is recommended to all users on all supported platforms.
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SimulaBeta 3.1.1 released
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Version History
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Tagging SimulaBeta 3.1.1.
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Final fixes for SimulaBeta 3.1.1.
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Specifying bioavailability of certain insulin species in sequencer.
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Misaligned colour marks
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Misaligned colour marks
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Version_History
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Version_History
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Correcting URL in readme file.
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Fixing a memory leak in the IPS plot handler.
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Several minor fixes, optimisations and updates.
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Handbook available
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Since SimulaBeta gets more and more complex we began to write a handbook. A first version is available from http://dx.doi.org/10.6084/m9.figshare.22578274 or here in SourceForge from https://sourceforge.net/projects/simulabeta/files/Documentation/.
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Misaligned colour marks
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Creating GUID for installer script.
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Several preparing steps for SimulaBeta 3.1.1.
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Preparing SimulaBeta 3.1.1 and fixing a bug in the LOREMOS GUI.
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Home
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Tagging SimulaBeta 3.1.0
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Basic two-way sensitivity analysis
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Implemented in SimulaBeta 3.1 (Challenger).
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Support for different units of measurement
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Implemented in SimulaBeta 3.1 (Challenger).
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Largely implemented in SimulaBeta 3.1 (Challenger).
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Flexible tolerance tests
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SimulaBeta has been published in version 3.1.0 (Challenger). This is a major upgrade that introduces a plethora of new features including statistics of simulated time series, a load, reference and modulation sequencer (LOREMOS) to simulate complex patterns of external influences on glucose homeostasis, sensitivity analysis in form of a disposition table and support for different units of measurement for insulin and glucose concentrations.
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SimulaBeta 3.1 published
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Version History
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Version History
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Minor updates.
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Minor updates.
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Final optimisations for SimulaBeta 3.1
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Fixing several bugs affecting Windows-based systems
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