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 .idea 2019-12-22 Evys Ancede Gallardo Evys Ancede Gallardo [6fc907] Change Biopython option to subprocess to run bl...
 calculate 2019-12-22 Evys Ancede Gallardo Evys Ancede Gallardo [6a6e60] Round option changed
 examples 2019-09-16 Evys Ancede Gallardo Evys Ancede Gallardo [07eead] Modifications of GUI and author format change o...
 ui 2019-09-16 Evys Ancede Gallardo Evys Ancede Gallardo [d88a3b] Cherry Picking at merge and matrix plot impleme...
 .gitignore 2019-12-22 Evys Ancede Gallardo Evys Ancede Gallardo [3eaef7] GUI modifications and all matrix calculations f...
 LICENSE 2019-09-16 eancedeg eancedeg [102cd7] Create LICENSE
 README.md 2020-01-09 eancedeg eancedeg [8c45b0] Authors and bibliographical references modifica...
 SeqDivA.py 2019-12-22 Evys Ancede Gallardo Evys Ancede Gallardo [470b14] Revert "Change Biopython option to subprocess t...
 requirements.txt 2019-12-22 Evys Ancede Gallardo Evys Ancede Gallardo [3eaef7] GUI modifications and all matrix calculations f...

Read Me

SeqDivA

Sequence Diversity Analysis

Authors

  • Evys Ancede-Gallardo (eancedeg@gmail.com)
  • Guillermin Agüero-Chapin (gaguero@gmail.com)

Sequence Diversity Analysis - SeqDivA version 1.0 is a python-based tool with a friendly GUI designed for Linux and Mac OS.

Utility: Run alignment algorithms (water, needle, and blast) to compare all-vs.-all protein, DNA, and RNA sequences. SeqDivA provides similarity, identity, and bit-score matrixes and dot plots to explore/illustrate the diversity (homology degree) of the sequences, enabling the delimitation of the twilight zone.

Installation Prerequisites:

  • matplotlib

  • numpy

  • pandas

  • pyqt

  • biopython

Installation:

  • Download SeqDivA at https://github.com/eancedeg/SeqDivA

  • decompress the “.zip or tar.gz” file

  • Load the graphical interface by executing python SeqDivA.py. Python 3.7 is recommended.

Authors:

  • Evys Ancede-Gallardo (eancedeg@gmail.com), Programa de Doctorado en Fisicoquímica Molecular, Facultad de Ciencias Exactas, Universidad Andrés Bello, Av. República 275, Santiago 8370146, Chile.

  • Guillermin Agüero-Chapin (gaguero@gmail.com), CIIMAR- Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, Portugal

Reference: Agüero-Chapin, G., Galpert, D., Molina-Ruiz, R., Ancede-Gallardo, E., Pérez-Machado, G., De la Riva, G. A., & Antunes, A. (2019). Graph Theory-Based Sequence Descriptors as Remote Homology Predictors. Biomolecules, 10(1), 26. https://doi.org/10.3390/biom10010026

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