Many Scid options and preferences (such as the board size, colors, fonts, and default settings) are adjustable from the [Options] menu. All these (and more, such as the last directory you loaded a database from and the sizes of some windows) are saved to an options file when you select Save Options from the Options menu. The options file is loaded whenever you start Scid.
If you use Windows, the options file is scid.opt in the directory where the Scid program file scid.exe is located. For users of Unix operating systems (such as Solaris or Linux) the file is ~/.scid/scidrc.
There may be a player name (or several names) for whom, whenever a game is loaded, you would like the main window chessboard to be displayed from the perspective of that player. You can configure a list of such names using My Player Names... from the [Options/Chessboard] menu. In the dialog box that appears, enter one player name on each line. Wildcard characters ("?" for exactly one character and "*" for a sequence of zero or more characters) can be used.
Scid has three basic fonts it uses in most of its windows, and you can customize all of them. They are called regular, small and fixed.
The fixed font should be a fixed-width (not proportional) font. It is used for the tree and crosstable windows.