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bbi law in JDesigner

2014-08-06
2014-08-07
  • Pier Andrea Serra

    Dear Sirs,
    first of all my compliments for this amazing software and your efforts for making SBW a useful toolchain. In my research I develop enzyme-based amperometric biosensors but I'm new in the simulation field. At moment I'm studying the oxygen dependence of oxydase-based biosensors and I've successfully simulated my experimental results with Jarnac and the BBI law. Do you have a corresponding example in JDesigner? I need just 2 substrates and 2 products (I.e. for the GLucose oxidase enzyme: GLucose + O2 -> Glucono Lactone H2O2).
    Thank you in advance for your availability.
    Sincerely yours,
    Pier Andrea Serra, University of Sassari, Italy.

     
  • Frank Bergmann

    Frank Bergmann - 2014-08-06

    Hello,

    it seems in Jdesinger you will have to spell out the equation, it is defined as such:

    bbi(S1,S2,Vm,Km1,Km2,Kia) = Vm * S1 * S2 / (Kia*Km2 + Km2*S1 + Km1*S2 + S1*S2)
    

    All formulas of Jarnac can be found in the SBW documentation folder under Jarnac Reference.

    I hope this helps,
    all the best
    Frank

     
  • Pier Andrea Serra

    Thank you Frank,
    your help has been very precious to me.
    Kindest regards,
    Pier Andrea.

     

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