Re: [SOSlib-devel] [SOSlib-discuss] Parameters for Sensitivity Analysis

[Rainer M. <ra...@tb...>]

Dear Will,

I guess, you referring to program Sense (Sense.exe in Windows) in the 
example folder.

In that case: yes, you are right.

In the "p" mode  you can choose one parameter and will get sensitivities 
to this parameter for one or more chosen variables.
In the "v" mode you can choose one variable (as above) and will get 
sensitivities of this variable to one ore more chosen parameter.s

  Variables are

* species, if their concentration is defined by reactions or SBML rate 
rules (and not if set set constant or defined by an assignment rule), or

* parameters if defined by a rate rule (and not if constant or defined 
by an assigment rule).

Please note that currently variable compartments are not handled 
correctly!! Thus I left them out in above description.

Ok?

Also note, that it would be very easy to just create your own little C 
program, specific to your requirements.

Using the current CVS version will also improve sensitivity analysis 
significantly! In 1.6.0 sensitivities are calculated w.r.t. all 
constants of the model, while in current CVS version sensitivities are 
calculated only for the chosen constants. However, I haven't adapted the 
example/Sense program to that improvement yet.
Furthermore current CVS version allows to calculate sensitivities w.r.t. 
to initial conditions of variables.

regards,
Rainer








Will Norman wrote:
> I am building a web-app that uses the SBML Solver library, and was 
> wondering what the acceptable parameters are for the two modes of 
> sensitivity analysis.
> 
> Here is what I am thinking, is this correct?
> 
> For Parameter:
> 
> Takes in a single parameter (either  variable or constant)
> 
> and one or more variable Species, Parameters or Compartments
> 
> For Variable:
> 
> Takes in a single variable Species, Parameter, or Compartment
> 
> and one or more variable or constant Parameters
> 
> Thanks for the clarification.
> 
> 
> 
> 
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