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|
From: <le...@us...> - 2008-06-24 10:53:28
|
Revision: 355
http://sbgn.svn.sourceforge.net/sbgn/?rev=355&view=rev
Author: lenov
Date: 2008-06-24 03:53:26 -0700 (Tue, 24 Jun 2008)
Log Message:
-----------
Modified Paths:
--------------
trunk/documents/specifications/EntityRelationship/Level1/sbgn_ER-level1.tex
Added Paths:
-----------
trunk/documents/specifications/EntityRelationship/Level1/images/
trunk/documents/specifications/EntityRelationship/Level1/images/sbgn-logo-rgb.eps
trunk/documents/specifications/EntityRelationship/Level1/images/sbgn-logo-rgb.jpg
trunk/documents/specifications/EntityRelationship/Level1/sbgn_ER-level1.pdf
Added: trunk/documents/specifications/EntityRelationship/Level1/images/sbgn-logo-rgb.eps
===================================================================
--- trunk/documents/specifications/EntityRelationship/Level1/images/sbgn-logo-rgb.eps (rev 0)
+++ trunk/documents/specifications/EntityRelationship/Level1/images/sbgn-logo-rgb.eps 2008-06-24 10:53:26 UTC (rev 355)
@@ -0,0 +1,9644 @@
@@ Diff output truncated at 100000 characters. @@
This was sent by the SourceForge.net collaborative development platform, the world's largest Open Source development site.
|
|
From: <le...@us...> - 2008-06-24 10:49:56
|
Revision: 354
http://sbgn.svn.sourceforge.net/sbgn/?rev=354&view=rev
Author: lenov
Date: 2008-06-24 03:49:50 -0700 (Tue, 24 Jun 2008)
Log Message:
-----------
Added Paths:
-----------
trunk/documents/specifications/EntityRelationship/Level1/sbgn_ER-level1.bib
trunk/documents/specifications/EntityRelationship/Level1/sbgn_ER-level1.tex
trunk/documents/specifications/EntityRelationship/Level1/sources/
trunk/documents/specifications/EntityRelationship/Level1/sources/front-page.tex
trunk/documents/specifications/EntityRelationship/Level1/sources/latex-macros.tex
trunk/documents/specifications/EntityRelationship/Level1/sources/latex-style.tex
trunk/documents/specifications/EntityRelationship/Level1/sources/preface.tex
Added: trunk/documents/specifications/EntityRelationship/Level1/sbgn_ER-level1.bib
===================================================================
--- trunk/documents/specifications/EntityRelationship/Level1/sbgn_ER-level1.bib (rev 0)
+++ trunk/documents/specifications/EntityRelationship/Level1/sbgn_ER-level1.bib 2008-06-24 10:49:50 UTC (rev 354)
@@ -0,0 +1,114 @@
+@Article{Cook:2001,
+ author = {Daniel L. Cook and J. F. Farley and S. J. Tapscott},
+ title = {A basis for a visual language for describing, archiving and analyzing functional
+models of complex biological systems.},
+ journal = {Genome Biology},
+ year = {2001},
+ volume = {2},
+ number = {4},
+ pages = {research0012.1-research0012.10.}
+}
+
+@article{Hucka:2003,
+ AUTHOR = {Hucka, M. and Finney, A. and Sauro, H.~M. and Bolouri, H.
+ and Doyle, J.~C. and Kitano, H. and Arkin, A.~P.
+ and Bornstein, B.~J. and Bray, D. and Cornish-Bowden, A.
+ and Cuellar, A.~A. and Dronov, S. and Gilles, E.~D.
+ and Ginkel, M. and Gor, V. and Goryanin, I.~I.
+ and Hedley, W.~J. and Hodgman, T.~C. and Hofmeyr, J.-H.
+ and Hunter, P.~J. and Juty, N.~S. and Kasberger, J.~L.
+ and Kremling, A. and Kummer, U. and Le Nov\`{e}re, N.
+ and Loew, L.~M. and Lucio, D. and Mendes, P. and Minch, E.
+ and Mjolsness, E.~D. and Nakayama, Y. and Nelson, M.~R.
+ and Nielsen, P.~F. and Sakurada, T. and Schaff, J.~C.
+ and Shapiro, B.~E. and Shimizu, T.~S. and Spence, H.~D.
+ and Stelling, J. and Takahashi, K. and Tomita, M.
+ and Wagner, J. and Wang, J.},
+ TITLE = {The {S}ystems {B}iology {M}arkup {L}anguage ({SBML}): A Medium
+ for Representation and Exchange of Biochemical Network Models},
+ JOURNAL = {Bioinformatics},
+ VOLUME = {19},
+ NUMBER = {4},
+ PAGES = {524-531},
+ YEAR = 2003
+}
+
+@Article{Kitano:2003,
+ author = {Hiroaki Kitano},
+ title = {A graphical notation for biochemical networks},
+ journal = {BioSilico},
+ year = {2003},
+ volume = {1},
+ pages = {169-176}
+}
+
+@Article{Kitano:2005,
+ author = {Hiroaki Kitano and Akira Funahashi and Yukiko Matsuoka and Kanae Oda},
+ title = {Using process diagrams for the graphical representation of biological networks},
+ journal = {Nature Biotechnology},
+ year = {2005},
+ volume = {23},
+ number = {8},
+ pages = {961--966}
+}
+
+@Article{Kohn:1999,
+ author = {Kurt W. Kohn},
+ title = {Molecular Interaction Map of the Mammalian Cell Cycle Control and DNA Repair Systems},
+ journal = {Molecular Biology of the Cell},
+ year = {1999},
+ volume = {10},
+ number = {8},
+ pages = {2703--2734}
+}
+
+@Article{Kohn:2006,
+ author = {Kurt W. Kohn and Mirit I. Aladjem and J. N. Weinstein and Y. Pommier},
+ title = {Molecular interaction maps of bioregulatory networks: A general rubric for systems biology},
+ journal = {Molecular Biology of the Cell},
+ year = {2006},
+ volume = {17},
+ number = {1},
+ pages = {1--13}
+}
+
+@InProceedings{Maimon:2001,
+ author = {Ron Maimon and Sam Browning},
+ title = {Diagrammatic notation and computational structure of gene networks},
+ booktitle = {Proceedings of the 2nd International Conference on Systems Biology},
+ year = {2001},
+ editor = {Hiroaki Kitano},
+ pages = {311--317},
+ address = {Madison, WI},
+ publisher = {Omnipress}
+}
+
+@Article{Moodie:2006,
+ author = {Stuart L. Moodie and Anatoly A. Sorokin and Igor Goryanin and Peter Ghazal},
+ title = {A Graphical Notation to Describe the Logical Interactions of Biological Pathways},
+ journal = {Journal of Integrative Bioinformatics},
+ year = {2006},
+ volume = {3},
+ pages = {36}
+}
+
+@Article{Pirson:2000,
+ author = {I. Pirson and N. Fortemaison and C. Jacobs and S. Dremier and J. E. Dumont and C. Maenhaut},
+ title = {The visual display of regulatory information and networks},
+ journal = {Trends in Cell Biology},
+ year = {2000},
+ volume = {10},
+ number = {10},
+ pages = {404--408}
+}
+
+@article{Chen:1976,
+ author = "Peter Pin-Shan S. Chen",
+ title = "The Entity-Relationship Model: Toward a Unified View of Data",
+ journal = "ACM Transactions on Database Systems",
+ volume = "1",
+ number = "1",
+ pages = "9--36",
+ year = "1976",
+ url = "citeseer.ist.psu.edu/519283.html"
+}
\ No newline at end of file
Added: trunk/documents/specifications/EntityRelationship/Level1/sbgn_ER-level1.tex
===================================================================
--- trunk/documents/specifications/EntityRelationship/Level1/sbgn_ER-level1.tex (rev 0)
+++ trunk/documents/specifications/EntityRelationship/Level1/sbgn_ER-level1.tex 2008-06-24 10:49:50 UTC (rev 354)
@@ -0,0 +1,55 @@
+% =============================================================================
+% Top-level latex file for the SBGN Process Diagram specification document.
+%
+% $HeadURL: https://sbgn.svn.sourceforge.net/svnroot/sbgn/trunk/documents/specifications/EntityRelationship/Level1/sbgn_ER-level1.tex $
+% =============================================================================
+
+\documentclass[11pt,oneside]{book}
+
+%% ----------------------------------------------------------------------------
+%% Layout customizations and macro definitions.
+%% ----------------------------------------------------------------------------
+
+\input{sources/latex-style}
+\input{sources/latex-macros}
+
+
+%% ----------------------------------------------------------------------------
+\begin{document}
+%% ----------------------------------------------------------------------------
+
+\frontmatter
+
+\input{sources/front-page}
+%\input{sources/preface}
+%\input{sources/toc}
+
+\mainmatter
+
+%\include{sources/introduction}
+%\include{sources/glyphs}
+%\include{sources/grammar}
+%\include{sources/layout}
+
+\appendix
+
+%\include{sources/examples}
+%\include{sources/refcard}
+%\include{sources/working}
+
+\backmatter
+
+\clearpage
+\bibliographystyle{unsrt}
+\bibliography{sbgn_ER-level1}
+
+
+%% ----------------------------------------------------------------------------
+\end{document}
+%% ----------------------------------------------------------------------------
+
+
+% The following is for [X]Emacs users. Please leave in place.
+% Local Variables:
+% TeX-master: t
+% End:
Added: trunk/documents/specifications/EntityRelationship/Level1/sources/front-page.tex
===================================================================
--- trunk/documents/specifications/EntityRelationship/Level1/sources/front-page.tex (rev 0)
+++ trunk/documents/specifications/EntityRelationship/Level1/sources/front-page.tex 2008-06-24 10:49:50 UTC (rev 354)
@@ -0,0 +1,87 @@
+% $HeadURL: https://sbgn.svn.sourceforge.net/svnroot/sbgn/trunk/documents/specifications/EntityRelationship/Level1/sources/front-page.tex $
+
+\begin{titlepage}
+
+\vspace*{0.75in}
+
+\begin{center}
+
+ \textbf{\sffamily\bfseries\huge
+ Systems Biology Graphical Notation:\\[0.3em]
+ Entity Relationship Level 1}
+
+\vspace*{0.5in}
+
+\large
+Draft of \sbgndate\\[0.25in]
+
+\cornersize{0.3}\ovalbox{\begin{minipage}{4.9in}\color{DarkRed}
+Disclaimer: This is a working draft of the SBGN Process Diagram
+Level~1 specification. It is not a normative document.
+\end{minipage}}
+
+\vspace{0.5in}
+
+% \textbf{\sffamily Editors}:\\[7pt]
+% \begin{tabular}{l>{\hspace*{15pt}}r}
+% Nicolas \lenov & \emph{EMBL European Bioinformatics Institute, UK}\\
+% Stuart Moodie & \emph{University of Edinburgh, UK}\\
+% Anatoly Sorokin & \emph{University of Edinburgh, UK}\\
+% Michael Hucka & \emph{California Institute of Technology, USA}\\[7pt]
+% \end{tabular}
+%
+% \vspace*{1em}
+% \textbf{\sffamily Principal Authors}:\\[7pt]
+% \begin{tabular}{l>{\hspace*{15pt}}r}
+% Nicolas \lenov & \emph{EMBL European Bioinformatics Institute, UK}\\
+% Stuart Moodie & \emph{University of Edinburgh, UK}\\
+% Anatoly Sorokin & \emph{University of Edinburgh, UK}\\
+% Michael Hucka & \emph{California Institute of Technology, USA}\\
+
+% Mirit Aladjem & \emph{National Cancer Institute, USA}\\
+
+% Falk Schreiber & \emph{Leibniz Institute IPK, Germany}\\
+% Emek Demir & \emph{MSKCC Computational Biology Center, USA}\\
+% Huaiyu Mi & \emph{SRI International, USA}\\
+% Yukiko Matsuoka & \emph{The Systems Biology Institute, Japan}\\
+% Katja Wegner & \emph{University of Hertfordshire, UK}\\
+% \multicolumn{2}{l}{\emph{and}}\\
+% Hiroaki Kitano & \emph{The Systems Biology Institute, Japan}\\
+% \end{tabular}
+
+\vfill
+
+\normalsize
+\begin{minipage}{5in}
+ \emph{To discuss any aspect of SBGN, please send your messages
+ to the mailing list \mailto{sbg...@sb...}. To get
+ subscribed to the mailing list or to contact us directly,
+ please write to \mailto{sbg...@sb...}.}
+\end{minipage}
+
+\vfill
+
+\centerline{\includegraphics[width=1.25in]{\SBGNLogoFile}}
+
+\end{center}
+
+\end{titlepage}
+
+% The title page is considered unnumbered and the next page after this
+% starts with the page number 1 (actually, i), but the duplication of page
+% number 1 confuses hyperref and leads to the following latex warning:
+%
+% "pdfTeX warning (ext4): destination with the same identifier
+% (name{page.1}) has been already used, duplicate ignored"
+%
+% The following change makes the title page have page number 1 and the next
+% page after that it becomes page ii. This is unorthodox, but seems not
+% completely unreasonable, and it avoids the confusing warning above.
+
+\setcounter{page}{2}
+
+
+% The following is for [X]Emacs users. Please leave in place.
+% Local Variables:
+% TeX-master: "../sbgn_ER-level1"
+% End:
Added: trunk/documents/specifications/EntityRelationship/Level1/sources/latex-macros.tex
===================================================================
--- trunk/documents/specifications/EntityRelationship/Level1/sources/latex-macros.tex (rev 0)
+++ trunk/documents/specifications/EntityRelationship/Level1/sources/latex-macros.tex 2008-06-24 10:49:50 UTC (rev 354)
@@ -0,0 +1,97 @@
+% $HeadURL: https://sbgn.svn.sourceforge.net/svnroot/sbgn/trunk/documents/specifications/ProcessDiagram/Level1/sources/latex-macros.tex $
+
+% ----------------------------------------------------------------
+% Definitions that change with releases of the document.
+% ----------------------------------------------------------------
+
+\newcommand{\sbgndate}{16 June, 2008}
+
+% ----------------------------------------------------------------
+% Common commands when writing.
+% ----------------------------------------------------------------
+
+\newcommand{\SBGNPDLone}{SBGN \PD Level~1\xspace}
+
+\newcommand{\PD}{Process Diagram\xspace}
+\newcommand{\PDs}{Process Diagrams\xspace}
+\newcommand{\ER}{Entity Relationship\xspace}
+\newcommand{\ERs}{Entity Relationship diagrams\xspace}
+\newcommand{\AF}{Activity Flow\xspace}
+\newcommand{\AFs}{Activity Flow diagrams\xspace}
+
+% The name of a glyph is emphasized. Note that this is only the
+% case when we talk about the glyph, not the biological concept
+% represented by the glyph.
+
+\newcommand{\glyph}[1] {\emph{#1}}
+\newcommand{\vglyph}[1] {\begin{sideways}\emph{#1}\end{sideways}}
+
+\newcommand{\ERonly} {\shabox{\textbf{ER only}}}
+\newcommand{\STonly} {\shabox{\textbf{ST only}}}
+\newcommand{\AFonly} {\shabox{\textbf{AF only}}}
+\newcommand{\NotER} {\shabox{\textbf{Not ER. AF and ST only}}}
+\newcommand{\NotAF} {\shabox{\textbf{Not AF. ST and ER only}}}
+
+\newcommand{\sbo} {Systems Biology Ontology\xspace}
+\newcommand{\sbourl} {\url{http://www.ebi.ac.uk/sbo/}\xspace}
+\newcommand{\sboid}[1] {\texttt{#1}}
+
+\newcommand{\lenov} {Le~Nov\`{e}re\xspace}
+\newcommand{\D} {\displaystyle}
+\newcommand{\tm} {\textsuperscript{\tiny{\texttrademark}}}
+
+\newcommand{\literalFont}[1]{\textup{\texttt{#1}}}
+\newcommand{\figureFont}[1]{\textsf{\textbf{#1}}}
+
+\newcommand{\link}[2] {\literalFont{\href{#1}{#2}}}
+\newcommand{\mailto}[1] {\link{mailto:#1}{#1}}
+
+\newcommand{\chap}[1] {Chapter~\protect\ref{chp:#1}\xspace}
+\newcommand{\sect}[1] {Section~\protect\ref{sec:#1}\xspace}
+\newcommand{\fig}[1] {Figure~\protect\vref{fig:#1}\xspace}
+\newcommand{\tab}[1] {Table~\protect\vref{tab:#1}\xspace}
+\newcommand{\eg} {e.g.,\xspace}
+\newcommand{\ie} {i.e.,\xspace}
+
+
+% ----------------------------------------------------------------
+% Commands for internal comments.
+% ----------------------------------------------------------------
+
+\newcommand\question[2]{{\color{red}[#1]}\marginpar{\color{red}\small\emph{#1: #2}}}
+\newcommand\comment[2]{\footnote{{\color{blue}[#2] #1}}}
+
+% Uncomment the definitions below to hide questions & comments.
+
+% \renewcommand\question[2]{}
+% \renewcommand\comment[2]{}
+
+
+% ----------------------------------------------------------------
+% SBGN logo.
+% ----------------------------------------------------------------
+
+\newcommand{\logofilebasename}{sbgn-logo-rgb}
+
+\ifpdf
+ % When creating PDFs, request the JPG format specifically,
+ % because the resulting quality in the PDF final output is best
+ % that way.
+ \newcommand{\SBGNLogoFile}{\logofilebasename.jpg}
+\else
+ \newcommand{\SBGNLogoFile}{\logofilebasename.eps}
+\fi
+
+% Graphics path adjustments to get the logo. The path setup is so
+% that the \includegraphics can find the logo file no matter where
+% the document is located (but obviously, it only works for
+% certain path combinations -- it's a total hack).
+
+\graphicspath{{.}{./images/}{../images/}}
+
+
+
+% The following is for [X]Emacs users. Please leave in place.
+% Local Variables:
+% TeX-master: "../sbgn_PD-level1"
+% End:
Added: trunk/documents/specifications/EntityRelationship/Level1/sources/latex-style.tex
===================================================================
--- trunk/documents/specifications/EntityRelationship/Level1/sources/latex-style.tex (rev 0)
+++ trunk/documents/specifications/EntityRelationship/Level1/sources/latex-style.tex 2008-06-24 10:49:50 UTC (rev 354)
@@ -0,0 +1,304 @@
+% $HeadURL$
+
+%% ----------------------------------------------------------------------------
+%% Load up packages we need.
+%% ----------------------------------------------------------------------------
+
+% Warning: more \usepackage commands are used later in this file.
+
+\usepackage[a4paper,centering,margin=1in,marginparwidth=0.75in]{geometry}
+\usepackage[utf8]{inputenc} % unicode support
+\usepackage{shadow}
+\usepackage{supertabular}
+\usepackage{multirow}
+\usepackage{multicol}
+\usepackage{enumitem}
+\usepackage{lscape}
+\usepackage{layout}
+\usepackage{array}
+\usepackage{fancybox}
+\usepackage{xspace}
+\usepackage{ifpdf}
+\usepackage{float}
+\usepackage[american]{varioref}
+\usepackage[normalem]{ulem}
+
+% Hyperref, xcolor, graphicx and possibly others have a flag "pdftex"
+% that needs to be used if pdflatex is being used. The following puts
+% these inside a conditional for that situation.
+
+\ifpdf
+ % Case: using pdflatex
+
+ \usepackage[pdftex]{graphicx}
+ \DeclareGraphicsExtensions{.pdf,.png}
+
+ % Options get even more complicated. If we're producing grayscale output,
+ % we don't want to bother with coloring links, but we still want to load
+ % hyperref so that its macros are defined (and we don't have to redefine
+ % everything that uses hyperref). So:
+
+ \usepackage[pdftex,breaklinks=true,colorlinks=true,plainpages=false,
+ pdfpagelabels,bookmarks=true,bookmarksopen=true,bookmarksopenlevel=2,
+ pdfhighlight=/O,linkcolor={RoyalBlue},citecolor={RoyalBlue},
+ pagecolor={RoyalBlue},urlcolor={RoyalBlue}]{hyperref}
+
+ \usepackage[pdftex,rgb,dvipsnames,svgnames,hyperref,table]{xcolor}
+
+\else
+ % Case: not using pdflatex
+
+ \usepackage{graphicx}
+ \DeclareGraphicsExtensions{.eps,.png}
+
+ \usepackage[breaklinks,plainpages=false,pdfpagelabels]{hyperref}
+ \usepackage[rgb,dvipsnames,svgnames,hyperref,table]{xcolor}
+
+\fi
+
+% Package 'rotating' needs to come after the others.
+
+\usepackage{rotating}
+
+% Booktabs for sharp-looking \toprule, \midrule, \bottomrule in tables.
+
+\usepackage{booktabs}
+\setlength{\cmidrulewidth}{0.3 pt}
+\setlength{\lightrulewidth}{0.3 pt}
+\setlength{\heavyrulewidth}{0.9 pt}
+
+
+%% ----------------------------------------------------------------------------
+%% Special customizations
+%% ----------------------------------------------------------------------------
+
+\makeatletter
+
+% Adjust bottom-of-page behavior and page line spacing.
+
+\raggedbottom
+\renewcommand{\baselinestretch}{0.98}
+
+% Numbers the paragraph, but does not lists them in the ToC
+
+\setcounter{secnumdepth}{4}
+\setcounter{tocdepth}{2}
+
+% Fix placement of figures & tables. This keeps latex from shoving big
+% floats to the end of a document when they are somewhat big, which it will
+% do even if you put [htb] as the argument.
+
+\setcounter{topnumber}{2}
+\renewcommand\topfraction{1.0}
+\setcounter{bottomnumber}{1}
+\renewcommand\bottomfraction{1.0}
+\renewcommand\textfraction{0.0}
+\renewcommand\floatpagefraction{0.9}
+
+% Adjustment to the spacing around tables and figures.
+
+\renewcommand{\intextsep}{2em}
+
+% This sets up Helvetica for headings. The font scaling is
+% because the default Helvetica size is too big.
+
+\RequirePackage{helvet}
+\def\Hv@scale{0.87}
+
+% The following sets up txtt for the typewriter font.
+
+\renewcommand{\ttdefault}{txtt}
+\DeclareMathAlphabet{\mathtt}{OT1}{txtt}{m}{n}
+\SetMathAlphabet{\mathtt}{bold}{OT1}{txtt}{b}{n}
+
+% The next bit is an adaption of code from ot1phv.fd and adapted to the txtt
+% fonts. The txtt fonts are just a tad too big, so this tries to rescale
+% them down a tiny bit. This isn't completely right because I couldn't
+% figure out the right syntax when the DeclareFontShape uses ssub below.
+% (Notice how the ones with ssub don't have the \Txtt@@scale factor.)
+
+\def\Txtt@scale{0.975}
+\edef\Txtt@@scale{s*[\csname Txtt@scale\endcsname]}%
+
+\DeclareFontFamily{OT1}{txtt}{\hyphenchar \font\m@ne}
+\DeclareFontShape{OT1}{txtt}{m}{n}{ %rebular
+ <-> \Txtt@@scale txtt%
+}{}
+\DeclareFontShape{OT1}{txtt}{m}{sc}{ %cap & small cap
+ <-> \Txtt@@scale txttsc%
+}{}
+\DeclareFontShape{OT1}{txtt}{m}{sl}{ %slanted
+ <-> \Txtt@@scale txttsl%
+}{}
+\DeclareFontShape{OT1}{txtt}{m}{it}{ %italic
+ <-> ssub * txtt/m/sl%
+}{}
+\DeclareFontShape{OT1}{txtt}{m}{ui}{ %unslanted italic
+ <-> ssub * txtt/m/sl%
+}{}
+\DeclareFontShape{OT1}{txtt}{b}{n}{ %bold
+ <-> \Txtt@@scale txbtt%
+}{}
+\DeclareFontShape{OT1}{txtt}{b}{sc}{ %bold cap & small cap
+ <-> \Txtt@@scale txbttsc%
+}{}
+\DeclareFontShape{OT1}{txtt}{b}{sl}{ %bold slanted
+ <-> \Txtt@@scale txbttsl%
+}{}
+\DeclareFontShape{OT1}{txtt}{b}{it}{ %bold italic
+ <-> ssub * txtt/b/sl%
+}{}
+\DeclareFontShape{OT1}{txtt}{b}{ui}{ %bold unslanted italic
+ <-> ssub * txtt/b/sl%
+}{}
+\DeclareFontShape{OT1}{txtt}{bx}{n}{ %bold extended
+ <-> ssub * txtt/b/n%
+}{}
+\DeclareFontShape{OT1}{txtt}{bx}{sc}{ %bold extended cap & small cap
+ <-> ssub * txtt/b/sc%
+}{}
+\DeclareFontShape{OT1}{txtt}{bx}{sl}{ %bold extended slanted
+ <-> ssub * txtt/b/sl%
+}{}
+\DeclareFontShape{OT1}{txtt}{bx}{it}{ %bold extended italic
+ <-> ssub * txtt/b/sl%
+}{}
+\DeclareFontShape{OT1}{txtt}{bx}{ui}{ %bold extended unslanted italic
+ <-> ssub * txtt/b/sl%
+}{}
+
+% This next set of commands uses the sectsty package to change
+% section labels to be in a sans-serif font and put the numbers
+% into the left margin.
+
+\usepackage{sectsty}
+\allsectionsfont{\sffamily\raggedright}
+\def\@seccntformat#1{\protect\makebox[0pt][r]{\csname the#1\endcsname\quad}}
+
+% The next definitions change the style of the section headings.
+
+\renewcommand{\section}{\@startsection%
+ {section}{1}{0pt}{-3ex \@plus -0.5ex \@minus -.2ex}%
+ {1ex}{\Large\bfseries\sffamily}}
+
+\renewcommand{\subsection}{\@startsection%
+ {subsection}{2}{0pt}{-2.5ex \@plus -1ex \@minus -.2ex}%
+ {1ex}{\large\bfseries\sffamily}}
+
+\renewcommand{\subsubsection}{\@startsection%
+ {subsubsection}{3}{0pt}{-1.5ex \@plus -1ex \@minus -.2ex}%
+ {0.8ex}{\slshape\normalsize\bfseries\sffamily}}
+
+\renewcommand{\paragraph}{\@startsection%
+ {paragraph}{4}{0pt}{-1.25ex \@plus -1ex \@minus -.2ex}%
+ {0.5ex}{\slshape\normalsize\sffamily}}
+
+% Below, we take out the heading embedded by the \tableofcontents
+% command so that we can control where it's put.
+
+\renewcommand\tableofcontents{%
+ \if@twocolumn
+ \@restonecoltrue\onecolumn
+ \else
+ \@restonecolfalse
+ \fi
+ \@starttoc{toc}%
+ \if@restonecol\twocolumn\fi
+}
+
+% The following was ripped out of caption.sty, version 1.4b.
+% Copyright (C) 1994-95 Harald Axel Sommerfeldt
+% The first few lines set up the parameters for the layout created
+% by this style file.
+
+\newcommand{\captionsize}{\small}
+\newcommand{\captionfont}{\captionsize\itshape}
+\newcommand{\captionlabelfont}{\captionsize\sffamily\bfseries\upshape}
+\newlength{\captionmargin}
+\setlength{\captionmargin}{6ex}
+
+\newsavebox{\as@captionbox}
+\newlength{\as@captionwidth}
+\newcommand{\as@normalcaption}[2]{%
+ #1 #2\par}
+\let\as@caption\as@normalcaption
+\newcommand{\as@centercaption}[2]{%
+ \parbox[t]{\as@captionwidth}{{\centering#1 #2\par}}}
+\let\as@shortcaption\as@centercaption
+\newcommand{\as@makecaption}[2]{%
+ \setlength{\leftskip}{\captionmargin}%
+ \setlength{\rightskip}{\captionmargin}%
+ \addtolength{\as@captionwidth}{-2\captionmargin}%
+ \renewcommand{\baselinestretch}{0.9}
+ \captionfont%
+ \sbox{\as@captionbox}{{\captionlabelfont #1:} #2}%
+ \ifdim \wd\as@captionbox >\as@captionwidth
+ \as@caption{{\captionlabelfont #1:}}{#2}%
+ \else%
+ \as@shortcaption{{\captionlabelfont #1:}}{#2}%
+ \fi}
+\renewcommand{\@makecaption}[2]{%
+ \vskip\abovecaptionskip%
+ \setlength{\as@captionwidth}{\linewidth}%
+ \as@makecaption{#1}{#2}%
+ \vskip\belowcaptionskip}
+\ifx\@makerotcaption\undefined
+\else
+ \typeout{\space\space\space\space\space\space\space\space\space
+ `rotating' package detected}
+ \renewcommand{\@makerotcaption}[2]{%
+ \renewcommand{\baselinestretch}{0.9}
+ \captionfont%
+ \sbox{\as@captionbox}{{\captionlabelfont #1:} #2}%
+ \ifdim \wd\as@captionbox > .8\vsize
+ \rotatebox{90}{%
+ \setlength{\as@captionwidth}{.8\textheight}%
+ \begin{minipage}{\as@captionwidth}%
+ \as@caption{{\captionlabelfont #1:}}{#2}%
+ \end{minipage}}\par
+ \else%
+ \rotatebox{90}{\usebox{\as@captionbox}}%
+ \fi
+ \hspace{12pt}}
+\fi
+\ifx\floatc@plain\undefined
+\else
+ \typeout{\space\space\space\space\space\space\space\space\space
+ `float' package detected}
+ \renewcommand\floatc@plain[2]{%
+ \setlength{\as@captionwidth}{\linewidth}%
+ \as@makecaption{#1}{#2}}
+ \ifx\as@ruled\undefined
+ \else
+ \renewcommand\floatc@ruled[2]{%
+ \setlength{\as@captionwidth}{\linewidth}%
+ \renewcommand{\baselinestretch}{0.9}
+ \captionfont%
+ \as@caption{{\captionlabelfont #1:}}{#2}}
+ \fi
+\fi
+
+% We define our own description environment for documenting SBGN glyphs.
+
+\newenvironment{glyphDescription}{%
+ \renewcommand{\descriptionlabel}[1]{\hspace{\labelsep}\textsf{\textbf{##1}}}%
+ \begin{description}}%
+ {\end{description}}
+
+\newcommand{\glyphSboTerm}{\item[SBO Term:]\mbox{}\newline}
+\newcommand{\glyphContainer}{\item[Container:]\mbox{}\newline}
+\newcommand{\glyphLabel}{\item[Label:]\mbox{}\newline}
+\newcommand{\glyphAux}{\item[Auxiliary items:]\mbox{}\newline}
+
+
+%% ----------------------------------------------------------------------------
+%% The end.
+%% ----------------------------------------------------------------------------
+
+\makeatother
+
+
+%%% Local Variables:
+%%% mode: latex
+%%% TeX-master: "../sbgn_PD-level1"
+%%% End:
Added: trunk/documents/specifications/EntityRelationship/Level1/sources/preface.tex
===================================================================
--- trunk/documents/specifications/EntityRelationship/Level1/sources/preface.tex (rev 0)
+++ trunk/documents/specifications/EntityRelationship/Level1/sources/preface.tex 2008-06-24 10:49:50 UTC (rev 354)
@@ -0,0 +1,22 @@
+% $HeadURL: https://sbgn.svn.sourceforge.net/svnroot/sbgn/trunk/documents/specifications/EntityRelationshi/Level1/sources/preface.tex $
+
+\chapter{Preface}
+
+\section*{Acknowledgements}
+
+The authors are grateful to all the attendees of the SBGN meetings, as well as to the subscribers of the \mailto{sbg...@sb...} mailing list.
+
+% The authors would like to acknowledge especially the help of Frank Bergmann, Sarala Dissanayake, Ralph Gauges, Peter Ghazal, Igor Goryanin and Lu Li. SM and AS would also like to acknowledge Igor Goryanin whose financial support and encouragement enabled us to commit the necessary time to the development of this specification.
+
+The development of SBGN was mainly supported by a grant from the Japanese \emph{New Energy and Industrial Technology Development Organization} (NEDO, \url{http://www.nedo.go.jp/}) and also benefited from the help of a Japan Partnering Award of the British \emph{Biotechnology and Biological Sciences Research Council} (BBSRC, \url{http://www.bbsrc.ac.uk/})
+
+\section*{Notes on typographical conventions}
+
+The concept represented by a glyph is written using a normal font, while a \glyph{glyph} means the SBGN visual representation of the concept.
+
+
+
+% The following is for [X]Emacs users. Please leave in place.
+% Local Variables:
+% TeX-master: "../sbgn_PD-level1"
+% End:
This was sent by the SourceForge.net collaborative development platform, the world's largest Open Source development site.
|
|
From: <le...@us...> - 2008-06-24 10:25:59
|
Revision: 353
http://sbgn.svn.sourceforge.net/sbgn/?rev=353&view=rev
Author: lenov
Date: 2008-06-24 03:25:55 -0700 (Tue, 24 Jun 2008)
Log Message:
-----------
Added Paths:
-----------
trunk/documents/specifications/EntityRelationship/Level1/README.txt
Added: trunk/documents/specifications/EntityRelationship/Level1/README.txt
===================================================================
--- trunk/documents/specifications/EntityRelationship/Level1/README.txt (rev 0)
+++ trunk/documents/specifications/EntityRelationship/Level1/README.txt 2008-06-24 10:25:55 UTC (rev 353)
@@ -0,0 +1,13 @@
+
+ Specification for the
+
+ ----------------------------------------
+ Systems Biology Graphical Notation (SBGN)
+ Entity Relationship Level 1
+ ----------------------------------------
+
+ For more information about SBGN, visit:
+ http://sbgn.org
+
+ Please join the sbgn-discuss mailing list by visiting
+ http://www.sbgn.org/Forums
This was sent by the SourceForge.net collaborative development platform, the world's largest Open Source development site.
|
|
From: <le...@us...> - 2008-06-24 10:23:57
|
Revision: 352
http://sbgn.svn.sourceforge.net/sbgn/?rev=352&view=rev
Author: lenov
Date: 2008-06-24 03:23:54 -0700 (Tue, 24 Jun 2008)
Log Message:
-----------
Added Paths:
-----------
trunk/documents/specifications/EntityRelationship/Level1/Makefile
Added: trunk/documents/specifications/EntityRelationship/Level1/Makefile
===================================================================
--- trunk/documents/specifications/EntityRelationship/Level1/Makefile (rev 0)
+++ trunk/documents/specifications/EntityRelationship/Level1/Makefile 2008-06-24 10:23:54 UTC (rev 352)
@@ -0,0 +1,16 @@
+# =============================================================================
+# Top-level Makefile for the SBGN Entity Relationship specification.
+#
+# $HeadURL: https://sbgn.svn.sourceforge.net/svnroot/sbgn/trunk/documents/specifications/EntityRelationship/Level1/Makefile $
+# =============================================================================
+
+MAIN = sbgn_ER-level1
+
+LATEX = pdflatex
+BIBTEX = bibtex
+
+all default:
+ $(LATEX) $(MAIN).tex
+ $(LATEX) $(MAIN).tex
+ $(BIBTEX) $(MAIN)
+ $(LATEX) $(MAIN).tex
This was sent by the SourceForge.net collaborative development platform, the world's largest Open Source development site.
|
|
From: <le...@us...> - 2008-06-24 10:10:56
|
Revision: 351
http://sbgn.svn.sourceforge.net/sbgn/?rev=351&view=rev
Author: lenov
Date: 2008-06-24 03:10:54 -0700 (Tue, 24 Jun 2008)
Log Message:
-----------
Added Paths:
-----------
trunk/documents/specifications/EntityRelationship/Level1/
This was sent by the SourceForge.net collaborative development platform, the world's largest Open Source development site.
|
|
From: <stu...@us...> - 2008-06-16 14:17:25
|
Revision: 350
http://sbgn.svn.sourceforge.net/sbgn/?rev=350&view=rev
Author: stumoodie
Date: 2008-06-16 07:17:23 -0700 (Mon, 16 Jun 2008)
Log Message:
-----------
Changed docuent date to be set manually. We need to do this as this is the only way of versioning the doc...
Modified Paths:
--------------
trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
trunk/documents/specifications/ProcessDiagram/Level1/sources/latex-macros.tex
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
===================================================================
(Binary files differ)
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/latex-macros.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/latex-macros.tex 2008-06-16 14:04:48 UTC (rev 349)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/latex-macros.tex 2008-06-16 14:17:23 UTC (rev 350)
@@ -4,7 +4,7 @@
% Definitions that change with releases of the document.
% ----------------------------------------------------------------
-\newcommand{\sbgndate}{\today}
+\newcommand{\sbgndate}{16 June, 2008}
% ----------------------------------------------------------------
% Common commands when writing.
This was sent by the SourceForge.net collaborative development platform, the world's largest Open Source development site.
|
|
From: <stu...@us...> - 2008-06-16 14:05:06
|
Revision: 349
http://sbgn.svn.sourceforge.net/sbgn/?rev=349&view=rev
Author: stumoodie
Date: 2008-06-16 07:04:48 -0700 (Mon, 16 Jun 2008)
Log Message:
-----------
Added figures and captions to examples and improved gene regulation example
Modified Paths:
--------------
trunk/documents/specifications/ProcessDiagram/Level1/examples/IFNGeneRef.svg
trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
trunk/documents/specifications/ProcessDiagram/Level1/sources/examples.tex
Modified: trunk/documents/specifications/ProcessDiagram/Level1/examples/IFNGeneRef.svg
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/examples/IFNGeneRef.svg 2008-06-15 22:22:25 UTC (rev 348)
+++ trunk/documents/specifications/ProcessDiagram/Level1/examples/IFNGeneRef.svg 2008-06-16 14:04:48 UTC (rev 349)
@@ -9,17 +9,30 @@
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+ width="586.81738"
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inkscape:version="0.45.1"
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- sodipodi:docbase="/home/stuart/sbgn_svn/sbgn/documents/specifications/ProcessDiagram/Level1/examples"
+ sodipodi:docbase="/home/smoodie/svn/sbgn/trunk/documents/specifications/ProcessDiagram/Level1/examples"
sodipodi:docname="IFNGeneRef.svg"
inkscape:output_extension="org.inkscape.output.svg.inkscape">
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+ transform="scale(0.8,0.8)" />
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Modified: trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
===================================================================
(Binary files differ)
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/examples.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/examples.tex 2008-06-15 22:22:25 UTC (rev 348)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/examples.tex 2008-06-16 14:04:48 UTC (rev 349)
@@ -1,20 +1,38 @@
\chapter{Complete examples}
The following diagrams present complete examples of SBGN Process Diagrams.
-[NB: We are working on the legends of those maps. Another example is coming, describing a Gene Regulatory Network]
+\begin{figure}[htb]
\begin{center}
\scalebox{0.5}{\includegraphics{examples/glycolysis}}
+\caption{Glycolysis. This example illustrates how SBGN can be used to describe metabolic pathways.}
\end{center}
+\end{figure}
+\begin{figure}[t]
\begin{center}
\scalebox{0.5}{\includegraphics{examples/insulin}}
+\caption{Insulin-like Growth Factor (IGF) signalling. This example shows the use of compartments and how details can be hidden by using a submap. The submap is shown in the next figure.}
\end{center}
+\end{figure}
+\begin{figure}[b]
\begin{center}
\scalebox{0.5}{\includegraphics{examples/MAPK}}
+\caption{A submap of the previous diagram showing the MAPK cascade.}
\end{center}
+\end{figure}
+\begin{figure}[htb]
\begin{center}
\scalebox{0.5}{\includegraphics{examples/muscle}}
+\caption{Neuronal/Miuscl signalling. A description of inter-cellular signalling using SBGN.}
\end{center}
+\end{figure}
+
+\begin{figure}[htb]
+\begin{center}
+\scalebox{0.5}{\includegraphics{examples/IFNGeneRef}}
+\caption{Activated STAT1$\alpha$ induction of the IRF1 gene. An example of gene regulation using logical operators.}
+\end{center}
+\end{figure}
This was sent by the SourceForge.net collaborative development platform, the world's largest Open Source development site.
|
|
From: <stu...@us...> - 2008-06-15 22:22:37
|
Revision: 348
http://sbgn.svn.sourceforge.net/sbgn/?rev=348&view=rev
Author: stumoodie
Date: 2008-06-15 15:22:25 -0700 (Sun, 15 Jun 2008)
Log Message:
-----------
Working version. Not finished.
Added Paths:
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trunk/documents/specifications/ProcessDiagram/Level1/examples/IFNGeneRef.svg
Added: trunk/documents/specifications/ProcessDiagram/Level1/examples/IFNGeneRef.svg
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This was sent by the SourceForge.net collaborative development platform, the world's largest Open Source development site.
|
|
From: <stu...@us...> - 2008-06-13 22:53:33
|
Revision: 347
http://sbgn.svn.sourceforge.net/sbgn/?rev=347&view=rev
Author: stumoodie
Date: 2008-06-13 15:53:31 -0700 (Fri, 13 Jun 2008)
Log Message:
-----------
Fixed spelling, typos, missing refs and reformatted figures and tables.
Specifically fixed tasks:
1993153
1993156
1993416
1993427
1993439
Modified Paths:
--------------
trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.bib
trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
trunk/documents/specifications/ProcessDiagram/Level1/sources/CVs.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/association.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/compartment.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/complex.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/genetic.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/grammar.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/introduction.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/layout.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/macromolecule.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/multimer.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/preface.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/semantics.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/sourceSink.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/stateVariable.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/submap.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/syntax.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/tag.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/transition.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/trigger.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/uncertain.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/working.tex
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.bib
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.bib 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.bib 2008-06-13 22:53:31 UTC (rev 347)
@@ -102,3 +102,13 @@
pages = {404--408}
}
+@article{Chen:1976,
+ author = "Peter Pin-Shan S. Chen",
+ title = "The Entity-Relationship Model: Toward a Unified View of Data",
+ journal = "ACM Transactions on Database Systems",
+ volume = "1",
+ number = "1",
+ pages = "9--36",
+ year = "1976",
+ url = "citeseer.ist.psu.edu/519283.html"
+}
\ No newline at end of file
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
===================================================================
(Binary files differ)
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/CVs.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/CVs.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/CVs.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -34,7 +34,7 @@
\label{fig:material-types-cv}
\end{figure}
-lThe material types are in contrast to the \emph{conceptual types} (see below). The distinction is that material types are about physical composition, while conceptual types are about roles. For example, a strand of RNA is a physical artifact, but its use as messenger RNA is a role.
+The material types are in contrast to the \emph{conceptual types} (see below). The distinction is that material types are about physical composition, while conceptual types are about roles. For example, a strand of RNA is a physical artifact, but its use as messenger RNA is a role.
\subsection{Entity Pool Node conceptual types}
@@ -95,7 +95,7 @@
\subsection{Physical characteristics of compartments}
\label{sec:physical-characteristics-cv}
-\SBGNPDLone defines a special unit of information for describing certain common physical characsteristics of compartments. \fig{physical-characteristics-cv} lists the particular values defined by \SBGNPDLone. The values correspond to the \sbo branch with identifier \sboid{SBO:0000255} (\emph{physical characteristic} under \emph{quantitative parameter}).
+\SBGNPDLone defines a special unit of information for describing certain common physical characteristics of compartments. \fig{physical-characteristics-cv} lists the particular values defined by \SBGNPDLone. The values correspond to the \sbo branch with identifier \sboid{SBO:0000255} (\emph{physical characteristic} under \emph{quantitative parameter}).
\begin{figure}[h]
\centering
@@ -125,7 +125,7 @@
\toprule
\textbf{Name} & \textbf{\rmfamily Label} & \textbf{SBO term} \\
\midrule
- cardinaliy & N:\# & SBO:0000364\\
+ cardinality & N:\# & SBO:0000364\\
\bottomrule
\end{tabular}
\caption{The format of the possible values for the
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/association.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/association.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/association.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -8,7 +8,7 @@
\begin{glyphDescription}
\item[SBO]\mbox{}\\ SBO:0000177 ! binding.
- \item[origin]\mbox{}\\ More than one \glyph{consumption} arcss (section \ref{sec:consumption}).
+ \item[origin]\mbox{}\\ More than one \glyph{consumption} arc (section \ref{sec:consumption}).
\item[target]\mbox{}\\ One \glyph{production} arc (section \ref{sec:production}).
\item[node]\mbox{}\\ An \glyph{association} between several entities is represented by a filled disc.
\end{glyphDescription}
@@ -26,7 +26,7 @@
\scalebox{0.3}{\includegraphics{examples/association-MPF}}
\end{center}
-The following example illustrates the association of a pentameric macromolecule (a nicotinic acetylcholine receptor) with a simple chemical (the local anesthetic chlorpromazin) in an unamed complex, in an ST diagram.
+The following example illustrates the association of a pentameric macromolecule (a nicotinic acetylcholine receptor) with a simple chemical (the local anesthetic chlorpromazin) in an unnamed complex, in an ST diagram.
\begin{center}
\scalebox{0.3}{\includegraphics{examples/association-unamed}}
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/compartment.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/compartment.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/compartment.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -25,7 +25,7 @@
information for instance about the physical environment, such as pH,
temperature or voltage, see \ref{sec:unitInfo}.
The center of the bounding box of a \glyph{unit of information} is
- located on the midline of the border of the compartment.
+ located on the mid-line of the border of the compartment.
\end{glyphDescription}
\begin{figure}[H]
@@ -36,7 +36,7 @@
\end{figure}
-It is important to note that a compartment never contains another compartment, but may surround it. Two ``adjacents'' compartments are not separated by one line, but by \textbf{two} lines. The following example represents a cell made up of a nucleus surrounded by the cytoplasm.
+It is important to note that a compartment never contains another compartment, but may surround it. Two ``adjacent'' compartments are not separated by one line, but by \textbf{two} lines. The following example represents a cell made up of a nucleus surrounded by the cytoplasm.
\begin{center}
\scalebox{0.3}{\includegraphics{examples/compartment-cell}}
@@ -48,8 +48,8 @@
\scalebox{0.3}{\includegraphics{examples/compartment-3comp}}
\end{center}
-To make drawing aestetically more pleasing and understandable, comparments are
-allowed to overlap each other visually, but it does not mean continment or
+To make drawing aesthetically more pleasing and understandable, compartments are
+allowed to overlap each other visually, but it does not mean containment or
surrounding.
The following diagram represents two equivalent
placement of compartments:
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/complex.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/complex.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/complex.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -9,7 +9,7 @@
\begin{glyphDescription}
\glyphSboTerm SBO:0000253 ! non-covalent complex
\glyphContainer A \glyph{complex} possesses its own container box
- surrounding the juxtaposed container boxes of its components. This container box is a rectangle with cut-corners (an octogonal box with sides of two different lengths.). The size of the cut-corners are adjusted so that there is no overlap between the container and the components.
+ surrounding the juxtaposed container boxes of its components. This container box is a rectangle with cut-corners (an octagonal box with sides of two different lengths.). The size of the cut-corners are adjusted so that there is no overlap between the container and the components.
\glyphLabel The identification of a \glyph{named complex}
is carried by a box containing a string of characters. The
characters may be distributed on several lines to improve
@@ -20,7 +20,7 @@
of information} (see section \ref{sec:unitInfo}). Those units of information can characterise a
domain, such as a binding site. Particular \glyph{units of information} carry the material type and the conceptual type of the macromolecules.
The center of the bounding box of a \glyph{unit of information} is
- located on the midline of the border of the complex. A \glyph{complex} may
+ located on the mid-line of the border of the complex. A \glyph{complex} may
carry a \glyph{clone marker} (see section~\ref{sec:cloneMarker}).
\end{glyphDescription}
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/genetic.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/genetic.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/genetic.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -15,7 +15,7 @@
\glyphAux A \glyph{genetic entity} can carry state variables (\sect{stateVariable}) that add information about its precise state. The state of a genetic entity is therefore defined as the vector of all its state variables. A state variable is represented by an ellipsoid container, with the long axis of the ellipsoid placed on the border of the \glyph{genetic entity}'s container as illustrated in \fig{genetic}. The label of the state variable (type of characteristic, nucleotide number) can be optionally written either within the \glyph{genetic entity} container, or next to the border of the state variable container, or within the variable's container itself.
-A \glyph{genetic information} can also carry one or several \glyph{units of information} (\sect{unitInfo}). These can characterise a \glyph{genetic entity}'s domain, such as a binding site, or an exon. Particular \glyph{units of information} carry the material type (\sect{material-types-cv}) and the conceptual type (\sect{conceptual-types-cv}) of the of the genetic entity. The center of the bounding box of a \glyph{unit of information} is located on the midline of the border of the \glyph{genetic entity}.
+A \glyph{genetic information} can also carry one or several \glyph{units of information} (\sect{unitInfo}). These can characterise a \glyph{genetic entity}'s domain, such as a binding site, or an exon. Particular \glyph{units of information} carry the material type (\sect{material-types-cv}) and the conceptual type (\sect{conceptual-types-cv}) of the of the genetic entity. The center of the bounding box of a \glyph{unit of information} is located on the mid-line of the border of the \glyph{genetic entity}.
A \glyph{genetic entity} may also carry a \glyph{clone marker}
(\sect{cloneMarker}).
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/grammar.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/grammar.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/grammar.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -7,7 +7,7 @@
to make a valid SBGN diagram. To do this, we must at the very least
define what glyphs can be connected to each other. This is called
syntax. Next, we must define rules over and above connection rules,
-such as whether duplicate symbols are permitted. In addition, we must define what the notation ``means'' --- how does it represent a biological pathway? This is semantcs, and it is essential if a reader is to understand a SBGN diagram without external help, and a writer is to create one that reflects his understanding of a biologiocal system.
+such as whether duplicate symbols are permitted. In addition, we must define what the notation ``means'' --- how does it represent a biological pathway? This is semantics, and it is essential if a reader is to understand a SBGN diagram without external help, and a writer is to create one that reflects his understanding of a biological system.
In this section we start off by describing the concepts of the
\PD{} notation. Next a detailed description of the syntax is provided
@@ -89,15 +89,15 @@
\begin{landscape}
\begin{figure}[p]
\begin{center}
-\includegraphics[width=0.9\linewidth]{images/sbgn_visual}
-\caption{UML model of SBGN visual representation. Class names shown in italics are Abstract classes and do not correspond to a Glyph. Classes in non-italicised script with the suffixes ``Node'' and ``Arc'' correspond to node and arc glyphs repectively.}
+\includegraphics[width=0.85\linewidth]{images/sbgn_visual}
+\caption{UML model of SBGN visual representation. Class names shown in italics are Abstract classes and do not correspond to a Glyph. Classes in non-italicised script with the suffixes ``Node'' and ``Arc'' correspond to node and arc glyphs respectively.}
\label{fig:sbgn_visual}
\end{center}
\end{figure}
\begin{figure}[p]
\begin{center}
-\includegraphics[width=\linewidth]{images/sbgn_conceptual}
+\includegraphics[width=0.85\linewidth]{images/sbgn_conceptual}
\caption{UML model of SBGN conceptual representation. The main difference here is that the model is non-redundant with only one instance of an EntityPool with a given identity. Each class has a mapping back to the Visual Layer.}
\label{fig:sbgn_conceptual}
\end{center}
@@ -151,7 +151,7 @@
%
ModulatableNode & modulatingNodes (I) \{0 \ldots *\} & Any number of nodes that modulate this one.& Abstract & Nodes that can be modulated and so are linked to the end of a modulation arc.\\\hline
%
-ModulatingNode & & & Abstract & Nodes that can modulate modulateable nodes. They are linked to the start of a modulating arc.\\\hline
+ModulatingNode & & & Abstract & Nodes that can modulate modulatable nodes. They are linked to the start of a modulating arc.\\\hline
%
CompartmentShape & name (I) & Name of compartment being defined. At present the name of the compartment is not restricted, i.e.\, a controlled vocabulary is not used. & Compartment & \\
& unitsOfInformation \{0 \ldots *\} & any number of Units of Information. & &\\\hline
@@ -310,7 +310,7 @@
%
EntityType & Name (I) & The name of the EntityType. & \multirow{2}{\desclen}{This is the type of the EntityPool.} & \multirow{2}{\mappinglen}{No direct maps to the visual layer. It is an implied attribute of the EntityPoolNode.}\\
& type (I) & Type of the Entity. One of: SimpleChemical, UnspeciedEntity, Complex, Macromolecule, and GeneticEntity. & & \\
- & annotations \{0 \ldots *\} & Annotation must be associated with the type and be general to all Entity Pool Node. If it were associated with the Sprecies then this would be synonomous with a state description. & & \\\hline
+ & annotations \{0 \ldots *\} & Annotation must be associated with the type and be general to all Entity Pool Node. If it were associated with the Species then this would be synonymous with a state description. & & \\\hline
%
Multimeric\-Entity\-Type & As EntityType & & An Entity that can form homo-multimeric complexes. All copies share the same attributes. & \\
& cardinality (I) & The number of subunits in the monomer. & & \\\hline
@@ -340,12 +340,12 @@
Annotation & prefix (I) & A classifier for the annotation. & & UnitOfInformation\\
& annotation & Annotation that is associated with a Entity\-Type or Compartment. & & \\\hline
%
-Process & processType (I) & One of: Unspecified, Dissociation, Association, Omitted Process, Uncertain Process. & & The type is specified by the type of Glyph used: ProcessNode, DossociationNode, AssociationNode, OmittedProcessNode, UndertainProcessNode.\\\hline
+Process & processType (I) & One of: Unspecified, Dissociation, Association, Omitted Process, Uncertain Process. & & The type is specified by the type of Glyph used: ProcessNode, DissociationNode, AssociationNode, OmittedProcessNode, UndertainProcessNode.\\\hline
%
-Output & process (I) & The process the is the output of. & & ProductionArc \\
- & product (I) & The Entity Pool Node that is the product of the process. & & \\\hline
+Output & process (I) & The EPN that the process is the output of. & & ProductionArc \\
+ & product (I) & The EPN that is the product of the process. & & \\\hline
%
-Input & substrate (I) & The Entity Pool Node that is the input to the process. & & ConsumptionArc \\
+Input & substrate (I) & The EPN that is the input to the process. & & ConsumptionArc \\
& process (I) & The process that this is the input of. & & ConsumptionArc \\\hline
%
Control & type (R) & The type of the control. One of Modulation, Stimulation, Inhibition, Trigger, Catalysis or LogicGate. & & ModulationArc \\\hline
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/introduction.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/introduction.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/introduction.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -28,9 +28,9 @@
\section{History of SBGN development}
\label{sec:history}
-The effort to create a well-defined visual notation was pioneered by Kurt Kohn with his Molecular Interaction Map (MIM), a notation defining symbols and syntax to describe the interactions of molecules~\cite{Kohn:1999}. MIM is essentially a variation of entity-relationship diagrams~\cite{need-ref}. Kohn's work was followed by numerous other attempts to define both alternative notations for diagramming cellular processes (\eg the work of Pirson and colleagues~\cite{Pirson:2000}, BioD~\cite{Cook:2001}, and others), as well as extensions of Kohn's notation (\eg the Diagrammatic Cell Language of Maimon and Browning~\cite{Maimon:2001}).
+The effort to create a well-defined visual notation was pioneered by Kurt Kohn with his Molecular Interaction Map (MIM), a notation defining symbols and syntax to describe the interactions of molecules~\cite{Kohn:1999}. MIM is essentially a variation of the entity-relationship diagrams~\cite{Chen:1976}. Kohn's work was followed by numerous other attempts to define both alternative notations for diagramming cellular processes (\eg the work of Pirson and colleagues~\cite{Pirson:2000}, BioD~\cite{Cook:2001}, and others), as well as extensions of Kohn's notation (\eg the Diagrammatic Cell Language of Maimon and Browning~\cite{Maimon:2001}).
-Kitano originated the idea of having multiple views of the \emph{same} model. This addresses two problems: no single view can satisfy the needs of all users, and a given view can only represent a subset of the semantics necessary to express biological knowledge. Kitano proposed the development of process diagrams, entity-relationship diagrams, timing charts (to decribe temporal changes in a system), and abstract flow charts~\cite{Kitano:2003}. The \PD notation was the first to be fully defined using a well-delineated set of symbols and syntax~\cite{Kitano:2005}. It lead to a desire to establish a unified standard for graphical representation of biochemical entities, and from this arose the current SBGN effort. Separately and roughly concurrently, other groups designed similar notations, for example the Edinburgh Pathway Notation~\cite{Moodie:2006}. All of these efforts began to attract attention as more emphasis in biological research was placed on networks of interactions and not just characterization of individual entities.
+Kitano originated the idea of having multiple views of the \emph{same} model. This addresses two problems: no single view can satisfy the needs of all users, and a given view can only represent a subset of the semantics necessary to express biological knowledge. Kitano proposed the development of process diagrams, entity-relationship diagrams, timing charts (to describe temporal changes in a system), and abstract flow charts~\cite{Kitano:2003}. The \PD notation was the first to be fully defined using a well-delineated set of symbols and syntax~\cite{Kitano:2005}. It lead to a desire to establish a unified standard for graphical representation of biochemical entities, and from this arose the current SBGN effort. Separately and roughly concurrently, other groups designed similar notations, for example the Edinburgh Pathway Notation~\cite{Moodie:2006}. All of these efforts began to attract attention as more emphasis in biological research was placed on networks of interactions and not just characterization of individual entities.
In 2005, thanks to funding from the Japanese agency \emph{The New Energy and Industrial Technology Development Organization} (NEDO, \url{http://www.nedo.go.jp/}), Kitano initiated the Systems Biology Markup Language project as a community effort. The first SBGN workshop was held in February 2006 in Tokyo, with over 30 participants from major organizations interested in this effort. From the in-depth discussions held during that meeting emerged a set of decisions that are the basis of the current SBGN specification. These decisions are:
@@ -50,7 +50,7 @@
\section{The three languages of SBGN}
\label{sec:languages}
-Readers may well wonder, why are there \emph{three} languages in SBGN? The reason is that this approach solves a problem that was found insurmountable any other way: attempting to include all relevant facets of a biological system in a single diagram causes the diagram to become hoplessly complicated and incomprehensible to human readers.
+Readers may well wonder, why are there \emph{three} languages in SBGN? The reason is that this approach solves a problem that was found insurmountable any other way: attempting to include all relevant facets of a biological system in a single diagram causes the diagram to become hopelessly complicated and incomprehensible to human readers.
The three different notations in SBGN correspond to three different \emph{views} of the same model. These views are representations of different classes of information, as follows:
@@ -71,7 +71,7 @@
\PDs{} can quickly become very complex. Moreover, when diagramming a biochemical network, one often wants to ignore the biochemical basis underlying the action of one entity on the activity of another. A common desire is to represent only the flow of activity between nodes, without representing the transitions in the states of the nodes. This is the motivation for the creation of the \AF view. \AFs permit the use of \glyph{modulation}, \glyph{stimulation} and \glyph{inhibition} and allow them to point to State/Entity nodes rather than process nodes. The \AF view is thus a hybrid between \PD and \ERs. It is particularly convenient for representing the effect of perturbations, whether genetic or environmental in nature.
-A recurring argument in SBGN deveopment is that these these three types of diagrams should be merged into one. Unfortunately, each view has such different meanings that merging them would compromise the robustness of the representation and destroy the mathematical integrity of the notation system. While having three different notations makes the overall system more complex, much of the complexity and increase in burden on learning is mitigated by reusing most of the same symbols in all three notations. It is primarily the syntax and semantics that change between the different views, reflecting fundamental differences in the underlying mathematics of what is being described.
+A recurring argument in SBGN development is that these these three types of diagrams should be merged into one. Unfortunately, each view has such different meanings that merging them would compromise the robustness of the representation and destroy the mathematical integrity of the notation system. While having three different notations makes the overall system more complex, much of the complexity and increase in burden on learning is mitigated by reusing most of the same symbols in all three notations. It is primarily the syntax and semantics that change between the different views, reflecting fundamental differences in the underlying mathematics of what is being described.
% 2008-06-06 <mh...@ca...>
% I don't think the following is needed in this section.
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/layout.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/layout.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/layout.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -1,4 +1,4 @@
-\chapter{General layout of a graph in SBGN}
+\chapter{Layout Guidelines for a Process Diagram}
\label{chp:layout}
\section{Introduction}
@@ -14,11 +14,11 @@
diagrams may reveal new insights. The arrangement of objects in a
diagram is called a \emph{layout}.
-SBGN diagrams should be easily recognisable not only by the used
+SBGN process diagrams should be easily recognisable not only by the used
glyphs but also by the general style of the layout. However, the
arrangement of the objects is a complex art in itself, and there is
no simple rule which can be applied to all cases. Therefore this
-section provides guidelines for the layout of SBGN diagrams, divided
+section provides guidelines for the layout of process diagrams, divided
into two categories:
\begin{enumerate}
\item requirements, i.\,e.~rules which must be fulfilled by a
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/macromolecule.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/macromolecule.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/macromolecule.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -15,7 +15,7 @@
\glyphAux A \glyph{macromolecule} can carry state variables that can add information about its state (\sect{stateVariable}). The state of a macromolecule is therefore defined as the vector of all its state variables. A state variable is represented by an ellipsoid container, with the long axis of the ellipsoid placed on the border of the \glyph{macromolecule}'s container as illustrated in \fig{macromolecule}. The label of the state variable (which can precise the type of characteristic represented by the state variable, residue type, residue number etc.) can be optionally written either within the \glyph{macromolecule} container, or next to the border of the state variable container, or within the state variable's container itself.
-A \glyph{macromolecule} can also carry one or several \glyph{units of information} (\sect{unitInfo}). The units of information can characterise a domain, such as a binding site. Particular \glyph{units of information} are available for describing the material type (\sect{material-types-cv}) and the conceptual type (\sect{conceptual-types-cv}) of a macromolecule. The center of the bounding box of a \glyph{unit of information} is located on the midline of the border of the macromolecule.
+A \glyph{macromolecule} can also carry one or several \glyph{units of information} (\sect{unitInfo}). The units of information can characterise a domain, such as a binding site. Particular \glyph{units of information} are available for describing the material type (\sect{material-types-cv}) and the conceptual type (\sect{conceptual-types-cv}) of a macromolecule. The center of the bounding box of a \glyph{unit of information} is located on the mid-line of the border of the macromolecule.
A \glyph{macromolecule} may also carry a \glyph{clone marker} (see section~\ref{sec:cloneMarker})
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/multimer.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/multimer.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/multimer.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -15,7 +15,7 @@
\glyphAux A \glyph{multimer} can carry state variables that can add information about its state (\sect{stateVariable}). The state of a multimer is therefore defined as the vector of all its state variables. A state variable is represented by an ellipsoid container, with the long axis of the ellipsoid placed on the border of the top container of the \glyph{multimer} as illustrated in \fig{multimer}. Note that a \glyph{state variable} carried by a multimer actually applies to each of the constituent monomers individually. If instead a state variable is meant apply to the whole multimeric assembly, a \glyph{macromolecule} (\sect{macromolecule}) should be used instead of \glyph{multimer}. An assembly containing some state variables applicable to the components, and others state variable applicable to the assembly (for instance opening of a channel and phosphorylation of each of its subunits) should be represented by a \glyph{complex} (\sect{complex}).
-A \glyph{multimer} can also carry one or several \glyph{units of information} (\sect{unitInfo}). The information can characterize a domain, such as a binding site. Particular \glyph{units of information} exist for describing the material type (\sect{material-types-cv}), the conceptual type (\sect{conceptual-types-cv}), and the cardinality (\sect{cardinality-cv}) of the multimer. Note that a \glyph{unit of information} carried by a multimer actually applies to each of the constituent monomers individually. If instead a \glyph{unit of information} should be applicable to the whole multimeric assembly, a \glyph{macromolecule} should be used (\sect{macromolecule}). An assembly containing unit of informations applying to the components, and others to the assembly should be represented by a \glyph{complex} (\sect{complex}). The center of the bounding box of a \glyph{unit of information} is located on the midline of the border of the top multimer container. (See \fig{multimer} for an example.)
+A \glyph{multimer} can also carry one or several \glyph{units of information} (\sect{unitInfo}). The information can characterize a domain, such as a binding site. Particular \glyph{units of information} exist for describing the material type (\sect{material-types-cv}), the conceptual type (\sect{conceptual-types-cv}), and the cardinality (\sect{cardinality-cv}) of the multimer. Note that a \glyph{unit of information} carried by a multimer actually applies to each of the constituent monomers individually. If instead a \glyph{unit of information} should be applicable to the whole multimeric assembly, a \glyph{macromolecule} should be used (\sect{macromolecule}). An assembly containing units of information applying to the components, and others to the assembly should be represented by a \glyph{complex} (\sect{complex}). The center of the bounding box of a \glyph{unit of information} is located on the mid-line of the border of the top multimer container. (See \fig{multimer} for an example.)
A \glyph{multimer} may also carry a \glyph{clone marker} (\sect{cloneMarker}).
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/preface.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/preface.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/preface.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -4,9 +4,9 @@
\section*{Acknowledgements}
-The authors are grateful to all the attendees of the SBGN meetings, as well as to the subscribers of the \mailto{sbg...@sb...} mailing list. The authors would like to acknowledge especially the help of Frank Bergmann, Sarala Dissanayake, Ralph Gauges, Peter Ghazal, Igor Goryanin and Lu Li. SM and AS would also like to acknowledge Igor Goryanin whose financial support and encouragement enabled us to commit the neccessary time to the development of this specification.
+The authors are grateful to all the attendees of the SBGN meetings, as well as to the subscribers of the \mailto{sbg...@sb...} mailing list. The authors would like to acknowledge especially the help of Frank Bergmann, Sarala Dissanayake, Ralph Gauges, Peter Ghazal, Igor Goryanin and Lu Li. SM and AS would also like to acknowledge Igor Goryanin whose financial support and encouragement enabled us to commit the necessary time to the development of this specification.
-The development of SBGN was mainly supported by a grant from the Japanese \emph{New Energy and Industrial Technology Development Organization} (NEDO, \url{http://www.nedo.go.jp/}) and also benefitted from the help of a Japan Partering Award of the British \emph{Biotechnology and Biological Sciences Research Council} (BBSRC, \url{http://www.bbsrc.ac.uk/})
+The development of SBGN was mainly supported by a grant from the Japanese \emph{New Energy and Industrial Technology Development Organization} (NEDO, \url{http://www.nedo.go.jp/}) and also benefited from the help of a Japan Partnering Award of the British \emph{Biotechnology and Biological Sciences Research Council} (BBSRC, \url{http://www.bbsrc.ac.uk/})
\section*{Notes on typographical conventions}
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/semantics.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/semantics.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/semantics.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -8,6 +8,8 @@
\begin{center}
+\tablecaption{Namespace scope definitions.}
+\label{tab:namespacedefs}
\begin{small}
\tablefirsthead{\hline
Namespace Scope & Entities affected & Notes\\\hline}
@@ -19,9 +21,7 @@
\multicolumn{3}{|r|}{\small\sl continued on next page}\\
\hline}
\tablelasttail{\hline}
-\tablecaption{Namespace scope definitions.}
-\label{tab:namespacedefs}
-\begin{supertabular}{|l|p{5cm}|p{4cm}|}\hline
+\begin{supertabular}{|l|p{5cm}|p{5cm}|}\hline
%
MapDiagram & CompartmentShape, SubMapDiagram, EquivalenceNode & \\\hline
%
@@ -40,21 +40,21 @@
\begin{center}
-\begin{small}
+\tablecaption{Duplication rules.}
+\label{tab:processduprules}
+\begin{footnotesize}
\tablefirsthead{\hline
Node & Can Duplicate? & Indication & Additional Rules\\\hline}
\tablehead{\hline
\multicolumn{4}{|l|}{\small\sl continued from previous page}\\
\hline\hline
- Node & Can Duplicate? & Indication & Additional Rules\\\hline\hline}
+ Node & Duplicate? & Indication & Additional Rules\\\hline\hline}
\tabletail{\hline
\multicolumn{4}{|r|}{\small\sl continued on next page}\\
\hline}
\tablelasttail{\hline}
-\tablecaption{Duplication rules.}
-\label{tab:processduprules}
-\begin{supertabular}{|l|c|p{5cm}|p{4cm}|}\hline
-% Node & Can Duplicate? & How & Additional Rules\\\hline
+\begin{supertabular}{|l|c|p{4cm}|p{3.5cm}|}\hline
+% Node & Duplicate? & How & Additional Rules\\\hline
CompartmentShape & N & & \\\hline
SimpleChemicalNode & Y & Clone Marker & \\\hline
UnspecifiedEntityNode & Y & Clone Marker & \\\hline
@@ -78,7 +78,7 @@
ORNode & Y & As LogicalOperatorNode & \\\hline
NOTNode & Y & As LogicalOperatorNode & \\\hline
\end{supertabular}
-\end{small}
+\end{footnotesize}
\end{center}
\subsection{State Variables}
@@ -149,7 +149,7 @@
\item Modulators that do not interact with each other in the above manner should be drawn as modulating different process nodes. Their affect is therefore additive.
\item At most one trigger can be assigned to a process. Two triggers
would imply an implicit Boolean AND or OR operator. For clarity only
- one trigger can be assigned to a process and such cmbinations must
+ one trigger can be assigned to a process and such combinations must
explicitly used the Boolean operators.
\item At most one catalysis can be assigned to a process. A catalysis
modulation implies that the exact biochemical mechanism underlying
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/sourceSink.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/sourceSink.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/sourceSink.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -22,7 +22,7 @@
but it is important to note that it does not actually represent a true
absence of everything or a physical void---it represents the absence of the
corresponding structures in the model, that is, the fact that these sources
-or sinks are conceptualy outside the scope of the diagram.
+or sinks are conceptually outside the scope of the diagram.
A frequently asked question is, why bother having an explicit symbol at
all? The reason is that one cannot simply use an arc that does not
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/stateVariable.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/stateVariable.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/stateVariable.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -50,7 +50,7 @@
\label{fig:state-var}
\end{figure}
-A \glyph{state variable} does not necessarily have to be a boolean-valued
+A \glyph{state variable} does not necessarily have to be a Boolean-valued
variable. For example, an ion channel can possess several conductance
states; a receptor can be inactive, active and desensitized; and so on. A
\glyph{state variable} ``ubiquitin'' can also carry numerical values
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/submap.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/submap.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/submap.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -8,7 +8,7 @@
\begin{glyphDescription}
\glyphSboTerm to be determined
-\glyphContainer The \glyph{submap} is represented as a square box, to remind that it is fundamentaly a process.
+\glyphContainer The \glyph{submap} is represented as a square box, to remind that it is fundamentally a process.
\glyphLabel The identification of the \glyph{submap} is carried by an unbordered box containing a string of
characters. The characters may be distributed on several lines to improve readability, although this is not mandatory. The label box has to be attached to the center of the container box.
\glyphAux A \glyph{submap} carries labeled terminals. When the submap is represented folded, those terminals are linked to external EPNs (section~\ref{sec:EPNs}) or containers (section~\ref{sec:CNs}). In the unfolded view, exposing the internal structure of the submap, a set of \glyph{tags} point to the corresponding internal EPNs (section~\ref{sec:EPNs}) or containers (section~\ref{sec:CNs}).
@@ -28,7 +28,7 @@
\scalebox{0.3}{\includegraphics{examples/submap-folded}}
\end{center}
-The following diagram represents an unfolded version of the submap. Here, anything outside the submap has disappeared, and the internal \glyph{tags} are not linked to the corresponding external \glyph{terminals}. Note the tag 5, linking the compartment ``mito'' of the submap to the to the compartment ``mito'' outside the submap. The compartment containing Glu6P is implicitely defined as the same than the compartment containing Glu and Fru6p. There is no ambiguity because if Glu and Fru6 were in different compartments, one of them should have been defined within the submap.
+The following diagram represents an unfolded version of the submap. Here, anything outside the submap has disappeared, and the internal \glyph{tags} are not linked to the corresponding external \glyph{terminals}. Note the tag 5, linking the compartment ``mito'' of the submap to the to the compartment ``mito'' outside the submap. The compartment containing Glu6P is implicitly defined as the same than the compartment containing Glu and Fru6p. There is no ambiguity because if Glu and Fru6 were in different compartments, one of them should have been defined within the submap.
\begin{center}
\scalebox{0.3}{\includegraphics{examples/submap-dissociated}}
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/syntax.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/syntax.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/syntax.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -1,9 +1,9 @@
\section{Syntax}
The syntax of SBGN State Transition diagrams is defined in the form of an incidence matrix.
-An incidence matrix has arcs as rows and nodes as colums. Each element of the matrix represents the role of an arc in connection to a node. Input (I) means that the arc can begin at that node. Output (O) indicates that the arc can end at that node. Numbers in parenthesis represent the maximum number of arcs of a particular type to have this specific connection role with the node. Empty cells means the arc is not able to connect to the node.
+An incidence matrix has arcs as rows and nodes as columns. Each element of the matrix represents the role of an arc in connection to a node. Input (I) means that the arc can begin at that node. Output (O) indicates that the arc can end at that node. Numbers in parenthesis represent the maximum number of arcs of a particular type to have this specific connection role with the node. Empty cells means the arc is not able to connect to the node.
-For simplicity Logical operators are treated as PNs.
+For simplicity Logical operators are treated as EPNs.
\subsection{SN connectivity definition}
\begin{tabular}{||c|c|c|c|c|c|c|c|c|c|c|c||}
@@ -24,7 +24,7 @@
\end{tabular}
-\subsection{PN connectivity definition}
+\subsection{EPN connectivity definition}
\begin{tabular}{||c|c|c|c|c|c|c|c|c|c|c||}
\hline
@@ -44,14 +44,14 @@
\subsection{Containment definition}
There are two EPN types which allows containment in SBGN: \glyph{compartment} and
-\glyph{complex}. Next table describe relationship between EPN/PN elements of SBGN
+\glyph{complex}. Next table describe relationship between EPN elements of SBGN
and these two containers. Plus sign means that the element is able to be
-containde within container. Empty cell means containment is not allowed.
+contained within container. Empty cell means containment is not allowed.
\begin{tabular}{||c|c|c||}
\hline
-$EPN/PN \backslash Containers$ &
+$EPN \backslash Containers$ &
\glyph{compartment}& \glyph{complex} \\ \hline
\glyph{compartment} & + & +\\ \hline
\glyph{complex} & & + \\ \hline
@@ -76,7 +76,7 @@
\subsection{Syntactic Rules}
-Indicence matrix, defining main part of the syntax, is too permissive.
+Incidence matrix, defining main part of the syntax, is too permissive.
Additional rules should be defined to make syntax definition more precise.
\begin{enumerate}
@@ -87,7 +87,7 @@
\item All \glyph{state variables} of the \glyph{macromolecule} should have
different names;
\item \glyph{Complex} should consists of different EPNs. If two or more
- elementns of the complex are identical they should be replaced by multimer.
+ elements of the complex are identical they should be replaced by multimer.
\item Identity includes not only name of the element but its state also.
\end{enumerate}
\item Sink/Source.
@@ -95,33 +95,33 @@
\item \glyph{source/sink} is allowed to have only one link attached to it. It
could be either \glyph{consumption} or \glyph{production} link.
\end{enumerate}
- \item Process. That rules are applicable to all PNs (\ref{sec:PNs})
+ \item Process. That rules are applicable to all EPNs (\ref{sec:PNs})
\begin{enumerate}
- \item PN should have nonzero number of \glyph{consumption} links.
- \item PN should have nonzero number of \glyph{production} links.
+ \item EPN should have nonzero number of \glyph{consumption} links.
+ \item EPN should have nonzero number of \glyph{production} links.
\item All substrates of the transition should be different. If several
copies of the same EPN are involved in the process, cardinality label of
\glyph{consumption} arc should be used.
- \item All producs of the transition should be different. If several copies
+ \item All products of the transition should be different. If several copies
of the same EPN are produced in the process, cardinality label of
\glyph{production} arc should be used.
- \item Once cardinality label set to one arc of the PN all other arcs should
+ \item Once cardinality label set to one arc of the EPN all other arcs should
make their cardinality visible, even if it is undefined. In a case
cardinality is undefined or unknown ``?'' should placed as cardinality label.
\item The EPN is not allowed to be a substrate and product of the same
process. This rule is applicable to cloned EPNs as well.
- \item PN should have only one \glyph{Catalysis} arc connected to it. If
- there more than one catalyst is known for the process several PNs should be
+ \item EPN should have only one \glyph{Catalysis} arc connected to it. If
+ there more than one catalyst is known for the process several EPNs should be
drawn.
- \item PN should have only one \glyph{Trigger} arc connected to it. If
- there more than one trigger is known for the process several PNs should be
+ \item EPN should have only one \glyph{Trigger} arc connected to it. If
+ there more than one trigger is known for the process several EPNs should be
drawn.
\end{enumerate}
\item \glyph{Association}
\begin{enumerate}
\item Composition of the \glyph{complex} or \glyph{multimer} produced by
\glyph{association} should be identical to set of \glyph{association} substrates.
- \item If \glyph{asociation} produces \glyph{complex}, than number of
+ \item If \glyph{association} produces \glyph{complex}, than number of
\glyph{consumption} arcs should be two or more.
\item If \glyph{association} produces \glyph{multimer}, than the only one
\glyph{consumption} arc is allowed. In that case if substrate is not a
@@ -136,7 +136,7 @@
\glyph{dissociation} should be identical to set of products of the process.
\item If \glyph{complex} is consumed by the \glyph{dissociation}, than the
process should have two or more \glyph{production} arcs.
- \item If \glyph{multimer} is splitted by \glyph{dissociation} process, than
+ \item If \glyph{multimer} is split by \glyph{dissociation} process, than
one or more \glyph{production} arcs should be connected to the process node.
\end{enumerate}
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/tag.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/tag.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/tag.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -11,7 +11,7 @@
\glyphContainer A \glyph{tag} is represented by a rectangle fused to an empty arrowhead, as illustrated in \fig{tag}. The symbol should only be linked to one and only one edge (\ie it should reference only one EPN or container).
-\glyphLabel A \glyph{tag} is idenfied by a label placed in an unbordered box containing a string of characters. The characters can be distributed on several lines to improve readability, although this is not mandatory. The label box must be attached to the center of the container. The label may spill outside of the container.
+\glyphLabel A \glyph{tag} is identified by a label placed in an unbordered box containing a string of characters. The characters can be distributed on several lines to improve readability, although this is not mandatory. The label box must be attached to the center of the container. The label may spill outside of the container.
\glyphAux A \glyph{tag} does not carry any auxiliary items.
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/transition.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/transition.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/transition.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -52,7 +52,7 @@
\scalebox{0.3}{\includegraphics{examples/transition-reversible}}
\end{center}
-When such a reversible process is assymetrically modulated, it should be represented by two different processes in State Transition. The following example illustrates the use of two \glyph{transition} nodes to represent the reversible activation of a G-protein coupled receptor. In the absence of any effector, an equilibrium exists between the inactive and active forms. The agonist stabilises the active form, while the inverse agonist stabilises the inactive form.
+When such a reversible process is asymmetrically modulated, it should be represented by two different processes in State Transition. The following example illustrates the use of two \glyph{transition} nodes to represent the reversible activation of a G-protein coupled receptor. In the absence of any effector, an equilibrium exists between the inactive and active forms. The agonist stabilises the active form, while the inverse agonist stabilises the inactive form.
\begin{center}
\scalebox{0.3}{\includegraphics{examples/transition-modulated}}
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/trigger.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/trigger.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/trigger.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -27,7 +27,7 @@
\scalebox{0.5}{\includegraphics{examples/trigger-genetic}}
\end{center}
-The example below describe the transport of calcium ions out of the endoplasmic reticulum. Without IP3 receptor, there is not calcium flux, therefore, one cannot use a \glyph{stimulation}. The trigger intead represents this absolute stimulation.
+The example below describe the transport of calcium ions out of the endoplasmic reticulum. Without IP3 receptor, there is not calcium flux, therefore, one cannot use a \glyph{stimulation}. The trigger instead represents this absolute stimulation.
\begin{center}
\scalebox{0.5}{\includegraphics{examples/trigger-transport}}
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/uncertain.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/uncertain.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/uncertain.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -10,7 +10,7 @@
\item[SBO]\mbox{}\\ To be determined
\item[origin]\mbox{}\\ One or several \glyph{consumption} arcs (section \ref{sec:consumption}) or one or several \glyph{production} arcs (section \ref{sec:production}).
\item[target]\mbox{}\\ One or several \glyph{production} arcs (section \ref{sec:production}).
- \item[node]\mbox{}\\ Uncertain processes are represented as a transition containing a questionmark.
+ \item[node]\mbox{}\\ Uncertain processes are represented as a transition containing a question mark.
\end{glyphDescription}
\begin{figure}[H]
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/working.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/working.tex 2008-06-13 20:51:20 UTC (rev 346)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/working.tex 2008-06-13 22:53:31 UTC (rev 347)
@@ -5,14 +5,14 @@
The problem of entities, such as macromolecules, spanning several compartments proved to be a challenge for the community involved in the development of SBGN Process Diagram Level 1. It was thus decided to leave it for a future Level. It turns out there is at the moment no obvious solution satisfactory for everyone. Three broad classes of solutions have been identified so far:
\begin{itemize}
-\item One can systematically locate an \glyph{EPN} in a given \glyph{compartment}, for instance a transmembrane receptor in a membrane. However, the reactions of this entity with entities represented by \glyph{EPN} in other compartments, such as extracellular ligands and second messenger systems, will create artifitial transport reactions.
+\item One can systematically locate an \glyph{EPN} in a given \glyph{compartment}, for instance a transmembrane receptor in a membrane. However, the reactions of this entity with entities represented by \glyph{EPN} in other compartments, such as extracellular ligands and second messenger systems, will create artificial transport reactions.
\item One can represent the domains of proteins in different compartments by \glyph{macromolecules}, and link all those macromolecules in a \glyph{complex} spanning several compartments. However, such a representation would be very confusing, implying that the domains are actually different molecules linked through non-covalent bonds.
\item On can accept \glyph{macromolecules} that span several compartments, and represent domains as \glyph{units of information}. Those \glyph{units of information} should then be located in given compartments. To make a full use of such a representation, one should then start and end connecting arcs on given \glyph{units of information}, something prohibited by the current specification.
\end{itemize}
\section{Logical combination of state variable values}
-The value of a \glyph{state variable} has to be perfectly defined in \SBGNPDLone. If a state variable can take the alternative values 'A', 'B' and 'C', one cannot attribute it values such as 'non-A', 'A or B', 'any' or 'none'. As a consequence some biochemical processus cannot be easily represented because of the very large number of state to enumerate. The decision to forbid such a boolean logic lies in the necessity of maintaining truth path all over an SBGN map.
+The value of a \glyph{state variable} has to be perfectly defined in \SBGNPDLone. If a state variable can take the alternative values 'A', 'B' and 'C', one cannot attribute it values such as 'non-A', 'A or B', 'any' or 'none'. As a consequence some biochemical processes cannot be easily represented because of the very large number of state to enumerate. The decision to forbid such a Boolean logic lies in the necessity of maintaining truth path all over an SBGN map.
\section{Non-chemical entity nodes}
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From: <stu...@us...> - 2008-06-13 20:51:27
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Revision: 346
http://sbgn.svn.sourceforge.net/sbgn/?rev=346&view=rev
Author: stumoodie
Date: 2008-06-13 13:51:20 -0700 (Fri, 13 Jun 2008)
Log Message:
-----------
Release130608 submitted to sbgn-discuss for comments.
Added Paths:
-----------
tags/release130608/
Copied: tags/release130608 (from rev 345, trunk)
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From: <le...@us...> - 2008-06-13 15:21:38
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Revision: 345
http://sbgn.svn.sourceforge.net/sbgn/?rev=345&view=rev
Author: lenov
Date: 2008-06-13 08:21:35 -0700 (Fri, 13 Jun 2008)
Log Message:
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Modified Paths:
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trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
===================================================================
(Binary files differ)
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From: <le...@us...> - 2008-06-13 15:21:14
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Revision: 344
http://sbgn.svn.sourceforge.net/sbgn/?rev=344&view=rev
Author: lenov
Date: 2008-06-13 08:21:12 -0700 (Fri, 13 Jun 2008)
Log Message:
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Modified Paths:
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trunk/documents/specifications/ProcessDiagram/Level1/sources/examples.tex
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/examples.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/examples.tex 2008-06-13 15:17:53 UTC (rev 343)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/examples.tex 2008-06-13 15:21:12 UTC (rev 344)
@@ -1,6 +1,7 @@
\chapter{Complete examples}
The following diagrams present complete examples of SBGN Process Diagrams.
+[NB: We are working on the legends of those maps. Another example is coming, describing a Gene Regulatory Network]
\begin{center}
\scalebox{0.5}{\includegraphics{examples/glycolysis}}
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From: <le...@us...> - 2008-06-13 15:17:55
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Revision: 343
http://sbgn.svn.sourceforge.net/sbgn/?rev=343&view=rev
Author: lenov
Date: 2008-06-13 08:17:53 -0700 (Fri, 13 Jun 2008)
Log Message:
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Modified Paths:
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trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
===================================================================
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From: <le...@us...> - 2008-06-13 15:17:16
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Revision: 342
http://sbgn.svn.sourceforge.net/sbgn/?rev=342&view=rev
Author: lenov
Date: 2008-06-13 08:17:10 -0700 (Fri, 13 Jun 2008)
Log Message:
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Modified Paths:
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trunk/documents/specifications/ProcessDiagram/Level1/sources/preface.tex
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/preface.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/preface.tex 2008-06-13 15:07:09 UTC (rev 341)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/preface.tex 2008-06-13 15:17:10 UTC (rev 342)
@@ -4,8 +4,10 @@
\section*{Acknowledgements}
-The authors are grateful to all the attendees of the SBGN meetings, as well as to the subscribers of the \mailto{sbg...@sb...} mailing list. The authors would like to acknowledge especially the help of Frank Bergmann, Sarala Dissanayake, Ralph Gauges, Peter Ghazal, Igor Goryanin and Lu Li. SM and AS would also like to acknowledge Igor Goryanin whose financial support and encouragement enabled us to commit the neccessary time to the development of this specification.
+The authors are grateful to all the attendees of the SBGN meetings, as well as to the subscribers of the \mailto{sbg...@sb...} mailing list. The authors would like to acknowledge especially the help of Frank Bergmann, Sarala Dissanayake, Ralph Gauges, Peter Ghazal, Igor Goryanin and Lu Li. SM and AS would also like to acknowledge Igor Goryanin whose financial support and encouragement enabled us to commit the neccessary time to the development of this specification.
+The development of SBGN was mainly supported by a grant from the Japanese \emph{New Energy and Industrial Technology Development Organization} (NEDO, \url{http://www.nedo.go.jp/}) and also benefitted from the help of a Japan Partering Award of the British \emph{Biotechnology and Biological Sciences Research Council} (BBSRC, \url{http://www.bbsrc.ac.uk/})
+
\section*{Notes on typographical conventions}
The concept represented by a glyph is written using a normal font, while a \glyph{glyph} means the SBGN visual representation of the concept.
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From: <le...@us...> - 2008-06-13 15:07:12
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Revision: 341
http://sbgn.svn.sourceforge.net/sbgn/?rev=341&view=rev
Author: lenov
Date: 2008-06-13 08:07:09 -0700 (Fri, 13 Jun 2008)
Log Message:
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Modified Paths:
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trunk/documents/specifications/ProcessDiagram/Level1/sources/preface.tex
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/preface.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/preface.tex 2008-06-13 12:50:41 UTC (rev 340)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/preface.tex 2008-06-13 15:07:09 UTC (rev 341)
@@ -4,7 +4,7 @@
\section*{Acknowledgements}
-The authors are grateful to all the attendees of the SBGN meetings, as well as to the subscribers of the \mailto{sbg...@sb...} mailing list. The authors would like to acknowledge especially the help of Frank Bergmann, Ralph Gauges, Peter Ghazal, Igor Goryanin and Lu Li, whether by by their technical input or financial support.
+The authors are grateful to all the attendees of the SBGN meetings, as well as to the subscribers of the \mailto{sbg...@sb...} mailing list. The authors would like to acknowledge especially the help of Frank Bergmann, Sarala Dissanayake, Ralph Gauges, Peter Ghazal, Igor Goryanin and Lu Li. SM and AS would also like to acknowledge Igor Goryanin whose financial support and encouragement enabled us to commit the neccessary time to the development of this specification.
\section*{Notes on typographical conventions}
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From: <le...@us...> - 2008-06-13 12:50:49
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Revision: 340
http://sbgn.svn.sourceforge.net/sbgn/?rev=340&view=rev
Author: lenov
Date: 2008-06-13 05:50:41 -0700 (Fri, 13 Jun 2008)
Log Message:
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Modified Paths:
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trunk/documents/specifications/ProcessDiagram/Level1/images/catalysis.eps
trunk/documents/specifications/ProcessDiagram/Level1/images/catalysis.pdf
trunk/documents/specifications/ProcessDiagram/Level1/images/catalysis.svg
trunk/documents/specifications/ProcessDiagram/Level1/images/inhibition.eps
trunk/documents/specifications/ProcessDiagram/Level1/images/inhibition.pdf
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trunk/documents/specifications/ProcessDiagram/Level1/images/modulation.pdf
trunk/documents/specifications/ProcessDiagram/Level1/images/modulation.svg
trunk/documents/specifications/ProcessDiagram/Level1/images/omitted.pdf
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trunk/documents/specifications/ProcessDiagram/Level1/images/stimulation.pdf
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trunk/documents/specifications/ProcessDiagram/Level1/images/trigger.eps
trunk/documents/specifications/ProcessDiagram/Level1/images/trigger.pdf
trunk/documents/specifications/ProcessDiagram/Level1/images/trigger.svg
trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
trunk/documents/specifications/ProcessDiagram/Level1/sources/and.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/association.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/catalysis.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/compartment.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/consumption.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/dissociation.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/equivalenceArc.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/inhibition.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/logicArc.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/modulation.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/multimer.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/not.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/omitted.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/or.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/production.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/stimulation.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/submap.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/transition.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/trigger.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/uncertain.tex
Modified: trunk/documents/specifications/ProcessDiagram/Level1/images/catalysis.eps
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/images/catalysis.eps 2008-06-13 09:22:00 UTC (rev 339)
+++ trunk/documents/specifications/ProcessDiagram/Level1/images/catalysis.eps 2008-06-13 12:50:41 UTC (rev 340)
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Modified: trunk/documents/specifications/ProcessDiagram/Level1/images/inhibition.pdf
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From: <le...@us...> - 2008-06-13 09:22:03
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http://sbgn.svn.sourceforge.net/sbgn/?rev=339&view=rev
Author: lenov
Date: 2008-06-13 02:22:00 -0700 (Fri, 13 Jun 2008)
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Deleted: trunk/documents/specifications/ProcessDiagram/Level1/images/compartment_overlapping.pdf
===================================================================
(Binary files differ)
Deleted: trunk/documents/specifications/ProcessDiagram/Level1/images/compartment_overlapping.png
===================================================================
(Binary files differ)
Deleted: trunk/documents/specifications/ProcessDiagram/Level1/images/compartment_overlapping.svg
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/images/compartment_overlapping.svg 2008-06-12 23:17:13 UTC (rev 338)
+++ trunk/documents/specifications/ProcessDiagram/Level1/images/compartment_overlapping.svg 2008-06-13 09:22:00 UTC (rev 339)
@@ -1,219 +0,0 @@
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[truncated message content] |
|
From: <le...@us...> - 2008-06-12 23:17:15
|
Revision: 338
http://sbgn.svn.sourceforge.net/sbgn/?rev=338&view=rev
Author: lenov
Date: 2008-06-12 16:17:13 -0700 (Thu, 12 Jun 2008)
Log Message:
-----------
Modified Paths:
--------------
trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
trunk/documents/specifications/ProcessDiagram/Level1/sources/compartment.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/complex.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/macromolecule.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/multimer.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/refcard.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/working.tex
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
===================================================================
(Binary files differ)
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/compartment.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/compartment.tex 2008-06-12 22:30:55 UTC (rev 337)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/compartment.tex 2008-06-12 23:17:13 UTC (rev 338)
@@ -28,9 +28,12 @@
located on the midline of the border of the compartment.
\end{glyphDescription}
-\begin{center}
-\scalebox{0.3}{\includegraphics{images/compartment}}
-\end{center}
+\begin{figure}[H]
+ \centering
+ \includegraphics[scale = 0.3]{images/compartment}
+ \caption{The \PD glyph for \glyph{compartment}.}
+ \label{fig:macromolecule}
+\end{figure}
It is important to note that a compartment never contains another compartment, but may surround it. Two ``adjacents'' compartments are not separated by one line, but by \textbf{two} lines. The following example represents a cell made up of a nucleus surrounded by the cytoplasm.
@@ -52,7 +55,7 @@
placement of compartments:
\begin{center}
-\scalebox{0.3}{\includegraphics{images/compartment_overlapping}}
+\scalebox{0.3}{\includegraphics{examples/compartment_overlapping}}
\end{center}
Overlapped (hidden) part of the compartment should not contain any object,
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/complex.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/complex.tex 2008-06-12 22:30:55 UTC (rev 337)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/complex.tex 2008-06-12 23:17:13 UTC (rev 338)
@@ -24,6 +24,10 @@
carry a \glyph{clone marker} (see section~\ref{sec:cloneMarker}).
\end{glyphDescription}
-\begin{center}
-\scalebox{0.3}{\includegraphics{images/complex}}
-\end{center}
+
+\begin{figure}[H]
+ \centering
+ \includegraphics[scale = 0.3]{images/complex}
+ \caption{The \PD glyph for \glyph{complex}.}
+ \label{fig:complex}
+\end{figure}
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/macromolecule.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/macromolecule.tex 2008-06-12 22:30:55 UTC (rev 337)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/macromolecule.tex 2008-06-12 23:17:13 UTC (rev 338)
@@ -13,7 +13,7 @@
\glyphLabel A \glyph{macromolecule} is identified by a label placed in an unbordered box containing a string of characters. The characters can be distributed on several lines to improve readability, although this is not mandatory. The label box must be attached to the center of the container. The label may spill outside of the container.
-\glyphAux A \glyph{macromolecule} can carry state variables that can add information about its state (\sect{stateVariable}). The state of a macromolecule is therefore defined as the vector of all its state variables. A state variable is represented by an ellipsoid container, with the long axis of the ellipsoid placed on the border of the \glyph{macromolecule}'s container as illustrated in \fig{macromolecule}. The label of the state variable (which can \underline{convey the type of characteristic}~\question{MH}{I don't understand this}, residue type, residue number) can be optionally written either within the \glyph{macromolecule} container, or next to the border of the state variable container, or within the state variable's container itself.
+\glyphAux A \glyph{macromolecule} can carry state variables that can add information about its state (\sect{stateVariable}). The state of a macromolecule is therefore defined as the vector of all its state variables. A state variable is represented by an ellipsoid container, with the long axis of the ellipsoid placed on the border of the \glyph{macromolecule}'s container as illustrated in \fig{macromolecule}. The label of the state variable (which can precise the type of characteristic represented by the state variable, residue type, residue number etc.) can be optionally written either within the \glyph{macromolecule} container, or next to the border of the state variable container, or within the state variable's container itself.
A \glyph{macromolecule} can also carry one or several \glyph{units of information} (\sect{unitInfo}). The units of information can characterise a domain, such as a binding site. Particular \glyph{units of information} are available for describing the material type (\sect{material-types-cv}) and the conceptual type (\sect{conceptual-types-cv}) of a macromolecule. The center of the bounding box of a \glyph{unit of information} is located on the midline of the border of the macromolecule.
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/multimer.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/multimer.tex 2008-06-12 22:30:55 UTC (rev 337)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/multimer.tex 2008-06-12 23:17:13 UTC (rev 338)
@@ -13,7 +13,7 @@
\glyphLabel A \glyph{multimer} has no identity on its own. However, the first of the monomers carries an identifying label. The label placed is placed in an unbordered box containing a string of characters. The characters can be distributed on several lines to improve readability, although this is not mandatory. The label box must be attached to the center of the top monomer's container. The label may spill outside of the container.
-\glyphAux A \glyph{multimer} can carry state variables that can add information about its state (\sect{stateVariable}). The state of a multimer is therefore defined as the vector of all its state variables. A state variable is represented by an ellipsoid container, with the long axis of the ellipsoid placed on the border of the top container of the \glyph{multimer} as illustrated in \fig{multimer}. Note that a \glyph{state variable} carried by a multimer actually applies to each of the constituent monomers individually. If instead a state variable is meant apply to the whole multimeric assembly, a \glyph{macromolecule} (\sect{macromolecule}) should be used instead of \glyph{multimer}. \uline{An assembly containing state variables applying to the components, and others to the assembly should be represented by a \glyph{complex} (\sect{complex}).}~\question{MH}{I don't understand this}
+\glyphAux A \glyph{multimer} can carry state variables that can add information about its state (\sect{stateVariable}). The state of a multimer is therefore defined as the vector of all its state variables. A state variable is represented by an ellipsoid container, with the long axis of the ellipsoid placed on the border of the top container of the \glyph{multimer} as illustrated in \fig{multimer}. Note that a \glyph{state variable} carried by a multimer actually applies to each of the constituent monomers individually. If instead a state variable is meant apply to the whole multimeric assembly, a \glyph{macromolecule} (\sect{macromolecule}) should be used instead of \glyph{multimer}. An assembly containing some state variables applicable to the components, and others state variable applicable to the assembly (for instance opening of a channel and phosphorylation of each of its subunits) should be represented by a \glyph{complex} (\sect{complex}).
A \glyph{multimer} can also carry one or several \glyph{units of information} (\sect{unitInfo}). The information can characterize a domain, such as a binding site. Particular \glyph{units of information} exist for describing the material type (\sect{material-types-cv}), the conceptual type (\sect{conceptual-types-cv}), and the cardinality (\sect{cardinality-cv}) of the multimer. Note that a \glyph{unit of information} carried by a multimer actually applies to each of the constituent monomers individually. If instead a \glyph{unit of information} should be applicable to the whole multimeric assembly, a \glyph{macromolecule} should be used (\sect{macromolecule}). \uline{An assembly containing unit of informations applying to the components, and others to the assembly should be represented by a \glyph{complex} (\sect{complex}).}~\question{MH}{I don't understand this} The center of the bounding box of a \glyph{unit of information} is located on the midline of the border of the top multimer container. (See \fig{multimer} for an example.)
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/refcard.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/refcard.tex 2008-06-12 22:30:55 UTC (rev 337)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/refcard.tex 2008-06-12 23:17:13 UTC (rev 338)
@@ -1,4 +1,4 @@
\chapter{Reference card}
Print this summary of SBGN symbols for a quick reference.
-\noindent\rotatebox{-90}{\scalebox{0.9}{\includegraphics{images/refcard.eps}}}
\ No newline at end of file
+\noindent\rotatebox{-90}{\scalebox{0.9}{\includegraphics{images/refcard}}}
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sources/working.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/working.tex 2008-06-12 22:30:55 UTC (rev 337)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/working.tex 2008-06-12 23:17:13 UTC (rev 338)
@@ -2,6 +2,18 @@
\section{Multicompartment entities}
+The problem of entities, such as macromolecules, spanning several compartments proved to be a challenge for the community involved in the development of SBGN Process Diagram Level 1. It was thus decided to leave it for a future Level. It turns out there is at the moment no obvious solution satisfactory for everyone. Three broad classes of solutions have been identified so far:
+
+\begin{itemize}
+\item One can systematically locate an \glyph{EPN} in a given \glyph{compartment}, for instance a transmembrane receptor in a membrane. However, the reactions of this entity with entities represented by \glyph{EPN} in other compartments, such as extracellular ligands and second messenger systems, will create artifitial transport reactions.
+\item One can represent the domains of proteins in different compartments by \glyph{macromolecules}, and link all those macromolecules in a \glyph{complex} spanning several compartments. However, such a representation would be very confusing, implying that the domains are actually different molecules linked through non-covalent bonds.
+\item On can accept \glyph{macromolecules} that span several compartments, and represent domains as \glyph{units of information}. Those \glyph{units of information} should then be located in given compartments. To make a full use of such a representation, one should then start and end connecting arcs on given \glyph{units of information}, something prohibited by the current specification.
+\end{itemize}
+
\section{Logical combination of state variable values}
+The value of a \glyph{state variable} has to be perfectly defined in \SBGNPDLone. If a state variable can take the alternative values 'A', 'B' and 'C', one cannot attribute it values such as 'non-A', 'A or B', 'any' or 'none'. As a consequence some biochemical processus cannot be easily represented because of the very large number of state to enumerate. The decision to forbid such a boolean logic lies in the necessity of maintaining truth path all over an SBGN map.
+
\section{Non-chemical entity nodes}
+
+The current specification cannot represent combinations of events and entities. For instance a variable ''voltage'' cannot be controlled by a difference of concentration between different entities, such as a given ion in both sides of a membrane.
This was sent by the SourceForge.net collaborative development platform, the world's largest Open Source development site.
|
|
From: <le...@us...> - 2008-06-12 22:30:56
|
Revision: 337
http://sbgn.svn.sourceforge.net/sbgn/?rev=337&view=rev
Author: lenov
Date: 2008-06-12 15:30:55 -0700 (Thu, 12 Jun 2008)
Log Message:
-----------
Modified Paths:
--------------
trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping_wrong.eps
trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping_wrong.pdf
trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping_wrong.png
Modified: trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping_wrong.eps
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping_wrong.eps 2008-06-12 22:28:56 UTC (rev 336)
+++ trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping_wrong.eps 2008-06-12 22:30:55 UTC (rev 337)
@@ -1,940 +1,1208 @@
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+%%Title: compartment_overlapping_wrong.eps
+%%CreationDate: Thu Jun 12 23:30:21 2008
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|
From: <le...@us...> - 2008-06-12 22:28:57
|
Revision: 336
http://sbgn.svn.sourceforge.net/sbgn/?rev=336&view=rev
Author: lenov
Date: 2008-06-12 15:28:56 -0700 (Thu, 12 Jun 2008)
Log Message:
-----------
Modified Paths:
--------------
trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping.eps
trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping.pdf
trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping.png
trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping.svg
Modified: trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping.eps
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping.eps 2008-06-12 22:18:34 UTC (rev 335)
+++ trunk/documents/specifications/ProcessDiagram/Level1/examples/compartment_overlapping.eps 2008-06-12 22:28:56 UTC (rev 336)
@@ -1,1521 +1,3368 @@
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From: <le...@us...> - 2008-06-12 22:18:35
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Revision: 335
http://sbgn.svn.sourceforge.net/sbgn/?rev=335&view=rev
Author: lenov
Date: 2008-06-12 15:18:34 -0700 (Thu, 12 Jun 2008)
Log Message:
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Added Paths:
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From: <le...@us...> - 2008-06-12 22:04:29
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Revision: 334
http://sbgn.svn.sourceforge.net/sbgn/?rev=334&view=rev
Author: lenov
Date: 2008-06-12 15:04:25 -0700 (Thu, 12 Jun 2008)
Log Message:
-----------
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|
|
From: <le...@us...> - 2008-06-12 07:32:00
|
Revision: 333
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Author: lenov
Date: 2008-06-12 00:31:58 -0700 (Thu, 12 Jun 2008)
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-----------
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\begin{tabular}{l>{\hspace*{15pt}}r}
Nicolas \lenov & \emph{EMBL European Bioinformatics Institute, UK}\\
Stuart Moodie & \emph{University of Edinburgh, UK}\\
-Anatoly Sorokin & \emph{University of Edinburgh, UK}\\[7pt]
+Anatoly Sorokin & \emph{University of Edinburgh, UK}\\
+Michael Hucka & \emph{California Institute of Technology, USA}\\[7pt]
\end{tabular}
\vspace*{1em}
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From: <le...@us...> - 2008-06-12 07:27:36
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Revision: 332
http://sbgn.svn.sourceforge.net/sbgn/?rev=332&view=rev
Author: lenov
Date: 2008-06-12 00:27:30 -0700 (Thu, 12 Jun 2008)
Log Message:
-----------
Added Paths:
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trunk/documents/specifications/ProcessDiagram/Level1/sources/refcard.tex
trunk/documents/specifications/ProcessDiagram/Level1/sources/working.tex
Added: trunk/documents/specifications/ProcessDiagram/Level1/sources/refcard.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/refcard.tex (rev 0)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/refcard.tex 2008-06-12 07:27:30 UTC (rev 332)
@@ -0,0 +1,4 @@
+\chapter{Reference card}
+Print this summary of SBGN symbols for a quick reference.
+
+\noindent\rotatebox{-90}{\scalebox{0.9}{\includegraphics{images/refcard.eps}}}
\ No newline at end of file
Added: trunk/documents/specifications/ProcessDiagram/Level1/sources/working.tex
===================================================================
--- trunk/documents/specifications/ProcessDiagram/Level1/sources/working.tex (rev 0)
+++ trunk/documents/specifications/ProcessDiagram/Level1/sources/working.tex 2008-06-12 07:27:30 UTC (rev 332)
@@ -0,0 +1,7 @@
+\chapter{Issues postponed to future levels}
+
+\section{Multicompartment entities}
+
+\section{Logical combination of state variable values}
+
+\section{Non-chemical entity nodes}
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From: <mh...@us...> - 2008-06-12 01:56:10
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Revision: 331
http://sbgn.svn.sourceforge.net/sbgn/?rev=331&view=rev
Author: mhucka
Date: 2008-06-11 18:56:03 -0700 (Wed, 11 Jun 2008)
Log Message:
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Latest PDF.
Modified Paths:
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trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
Modified: trunk/documents/specifications/ProcessDiagram/Level1/sbgn_PD-level1.pdf
===================================================================
(Binary files differ)
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