Re: [Samtools-help] support to CRAM gzip [EXT]

[James B. <jk...@sa...>]

On Wed, Jul 05, 2023 at 03:11:50PM +0200, Adrian wrote:
> I noticed samtools works perfectly fine with gzip SAM and BAM files, but it
> does not work (to my knowledge) with gzip CRAM. Is there any reason for
> this? Is there any plan to implement support to gzip CRAM directly?

CRAM is already superior compression to gzip, so running gzip on the
CRAM will give minimal if any benefit.

James

-- 
James Bonfield (jk...@sa...)
The Sanger Institute, Hinxton, Cambs, CB10 1SA


-- 
 The Wellcome Sanger Institute is operated by Genome Research 
 Limited, a charity registered in England with number 1021457 and a 
 company registered in England with number 2742969, whose registered 
 office is Wellcome Sanger Institute, Wellcome Genome Campus, 
 Hinxton, CB10 1SA.