From: Robert D. <rm...@sa...> - 2018-02-12 17:14:41
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BCFtools 1.7 is now available from GitHub and SourceForge (Samtools and HTSlib 1.7 were previously released on 26th January). https://sourceforge.net/projects/samtools/ https://github.com/samtools/bcftools/releases/tag/1.7 The main changes are listed below: ------------------------------------------------------------------------------ bcftools - changes v1.7 ------------------------------------------------------------------------------ * `-i, -e` filtering: Major revamp, improved filtering by FORMAT fields and missing values. New GT=ref,alt,mis etc keywords, check the documentation for details. * `query`: Only matching expression are printed when both the -f and -i/-e expressions contain genotype fields. Note that this changes the original behaviour. Previously all samples were output when one matching sample was found. This functionality can be achieved by pre-filtering with view and then streaming to query. Compare bcftools query -f'[%CHROM:%POS %SAMPLE %GT\n]' -i'GT="alt"' file.bcf and bcftools view -i'GT="alt"' file.bcf -Ou | bcftools query -f'[%CHROM:%POS %SAMPLE %GT\n]' * `annotate`: New -k, --keep-sites option * `consensus`: Fix --iupac-codes output * `csq`: Homs always considered phased and other fixes * `norm`: Make `-c none` work and remove `query -c` * `roh`: Fix errors in the RG output * `stats`: Allow IUPAC ambiguity codes in the reference file; report the number of missing genotypes * `+fill-tags`: Add ExcHet annotation * `+setGt`: Fix bug in binom.test calculation, previously it worked only for nAlt<nRef! * `+split`: New plugin to split a multi-sample file into single-sample files in one go * Improve python3 compatibility in plotting scripts Rob Davies rm...@sa... The Sanger Institute http://www.sanger.ac.uk/ Hinxton, Cambs., Tel. +44 (1223) 834244 CB10 1SA, U.K. Fax. +44 (1223) 494919 -- The Wellcome Sanger Institute is operated by Genome Research Limited, a charity registered in England with number 1021457 and a company registered in England with number 2742969, whose registered office is 215 Euston Road, London, NW1 2BE. |