Follow RNA-Seq Assembly
Other Useful Business Software
Deliver secure remote access with OpenVPN.
OpenVPN's products provide scalable, secure remote access — giving complete freedom to your employees to work outside the office while securely accessing SaaS, the internet, and company resources.
Rate This Project
Login To Rate This Project
User Reviews
-
Bridger is an efficient de novo transcriptome assembler for RNA-Seq data. It expects as input RNA-Seq reads (single or paired) in fasta or fastq format, outputs all transcripts in fasta format, without using a reference genome. Briefly, it works in two steps: First, Bridger partitions the sequence data into many individual splicing graphs, each capturing the full transcriptional complexity at a given gene or no more than a few genes. Then, for each splicing graph, Bridger uses a rigorous mathematical model called minimum path cover to search an optimal set of paths (transcripts) that can be supported by sequence data and could explain all observed splicing events of each locus.