REDItools are python scripts developed with the aim to study RNA editing at genomic scale by next generation sequencing data. RNA editing is a post-transcriptional phenomenon involving the insertion/deletion or substitution of specific bases in precise RNA localizations. In human, RNA editing occurs by deamination of cytosine to uridine (C-to-U) or mostly by the adenosine to inosine (A-to-I) conversion through ADAR enzymes. A-to-I substitutions may have profound functional consequences and have been linked to a variety of human diseases including neurological and neurodegenerative disorders or cancer. NGS technologies offer a unique opportunity to investigate RNA editing. REDItools are simple python scripts conceived to investigate RNA editing at large-scale.
REDItools are now hosted at https://github.com/BioinfoUNIBA/REDItools
Features
- RNA editing
Categories
Bio-InformaticsLicense
MIT LicenseFollow reditools
User Reviews
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Amazing, straightforward tool for RNA editing detection! Great support form the developers.