From: Robert C. <cha...@cg...> - 2019-11-25 17:54:03
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I would also be keen to be involved in discussions about supporting glycopeptide data. Robert On 11/22/2019 11:21 AM, Zaia, Joseph wrote: > > Dear All, > > I would like to initiate discussion for expanding the use cases for > proteomics to include complex protein glycosylation. Glycosylation is > as a rule heterogeneous, with 30 or so glycoforms per glycosite. In > addition, the glycan dissociates during tandem MS experiments. The > software and data standards need to be expanded to include the > glycosylation size, heterogeneity, and tandem MS dissociation. At > present, quantitative software (Skyline and others) do not recognize > glycosylation. Without this recognition the quantitative tools > developed for peptides cannot be adapted without tedious effort on the > part of the user. Therefore, there is need to expand the manner by > which peptides are represented informatically. It is important that > glycopeptides be included in the use cases for mzIdentML and mzQuant. > It is also important that spectral library generating software be > expanded to allow glycosylated peptides to facilitate use of data > independent experiments for glycoproteins. > > Would it be possible for me to communicate these ideas at the PSI > Workshop in San Diego? > > Thank you. > > Joe Zaia > > *From:* Jones, Andy <And...@li...> > *Sent:* Thursday, November 21, 2019 11:29 AM > *To:* psi...@eb...; ps...@eb...; Mass spectrometry > standard development <psi...@li...>; > psi...@li...; Co...@go... > *Subject:* [Psidev-pi-dev] PSI2020 - Save the Date > > Hi all, > > We are pleased to announce that the 2020 Annual workshop for the > Proteomics Standards Initiative (PSI) will take place in San Diego > USA, Mon 23^rd to Thurs 26^th March 2020. The workshop will focus on > developing data standards related to mass spectrometry for spectral > libraries, the universal spectrum identifier, quality control and > capturing study metadata, and in the molecular interactions side on > mapping standards to Cytoscape. We will also be welcoming the new PSI > work group – Intrinsically Disordered Proteins (IDP). > > Please save the date if you might be interested to attend, we are > always pleased to welcome new groups into the PSI. The registration > page will be made available in the coming weeks. > > Best wishes > > Andy Jones on behalf of the PSI steering committee > > > _______________________________________________ > Psi-announce mailing list > Psi...@eb... > https://listserver.ebi.ac.uk/mailman/listinfo/psi-announce -- Robert Chalkley PhD Adjunct Professor Genentech Hall, N474A Tel: 415 476 5189 Fax: 415 502 1655 Mass Spectrometry Facility University of California San Francisco 600 16th Street, Genentech Hall, suite N472A San Francisco, CA 94143-2240 |