GOA NTNU_SB has used F8VPM9 for annotation to a mouse gene; MGI needs this in the PRO file to add to our gpi so we can load this annotation; PMID:15778499
Contact Astrid Lægreid astrid.lagreid@ntnu.no (in charge of NTNU annotation group
The first protein is identical to an existing PRO term, so I added the PMID to that term and made the TrEMBL-based accession an alt_id to the existing Swiss-Prot based PRO term. The second is an isoform of an existing PRO term, and defined accordingly. The third is a sequence variant of an existing isoform, and again defined accordingly.
[Term]
id: PR:Q03172
alt_id: PR:F8VPM9
name: zinc finger protein 40 (mouse)
def: "A zinc finger protein 40 that is encoded in the genome of mouse." [PRO:DNx, OMA:Q03172, PMID:15778499]
comment: Category=organism-gene.
synonym: "mHIVEP1" EXACT PRO-short-label [PRO:DNx]
synonym: "alpha A-CRYBP1 (mouse)" EXACT [UniProtKB:Q03172]
synonym: "alpha A-crystallin-binding protein 1 (mouse)" EXACT [UniProtKB:Q03172]
synonym: "alpha A-crystallin-binding protein I (mouse)" EXACT [UniProtKB:Q03172]
synonym: "transcription factor alphaA-CRYBP1 (mouse)" EXACT [UniProtKB:Q03172]
synonym: "Cryabp1" RELATED [UniProtKB:Q03172]
synonym: "Znf40" RELATED [UniProtKB:Q03172]
xref: UniProtKB:Q03172
intersection_of: PR:000008604 ! zinc finger protein 40
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
relationship: has_gene_template MGI:96100 ! Hivep1 (mouse)
relationship: has_canonical_sequence UniProtKB:Q03172 ! Q03172-1
[Term]
id: PR:D3YWT3
name: transcription factor 7-like 2 isoform D3YWT3 (mouse)
def: "A transcription factor 7-like 2 (mouse) that is a translation product of some mRNA giving rise to a protein with the amino acid sequence represented by UniProtKB:D3YWT3." [PRO:DNx, UniProtKB:D3YWT3, PMID:20044351]
comment: Category=organism-sequence.
synonym: "mTCF7L2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:D3YWT3
is_a: PR:Q924A0 ! transcription factor 7-like 2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus
[Term]
id: PR:A2AHT3
name: calsenilin isoform 3 sequence variant G41R (mouse)
def: "A calsenilin isoform 3 (mouse) that has an Arg residue at the position equivalent to Gly-41 of the amino acid sequence represented by UniProtKB:Q9QXT8-3. UniProtKB:Q9QXT8-3, Gly-41, CHEBI:29952." [PRO:DAN, PMID:11792319]
comment: Category=organism-sequence.
synonym: "mKCNIP3/iso:3/var:G41R" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9QXT8-3, Gly-41, CHEBI:29952" EXACT PRO-proteoform-std [PRO:DNx]
xref: UniProtKB:A2AHT3
is_a: PR:000036314 ! calsenilin (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus
If you would like to refer to this comment somewhere else in this project, copy and paste the following link:
Same group annotated to D3YWT3; need to move into PRO; using PMID:20044351
Also used A2AHT3 using PMID:11792319 and A2AEW1 using PMID:16936731
Last edit: Harold J. Drabkin 2019-03-22
The first protein is identical to an existing PRO term, so I added the PMID to that term and made the TrEMBL-based accession an alt_id to the existing Swiss-Prot based PRO term. The second is an isoform of an existing PRO term, and defined accordingly. The third is a sequence variant of an existing isoform, and again defined accordingly.
[Term]
id: PR:Q03172
alt_id: PR:F8VPM9
name: zinc finger protein 40 (mouse)
def: "A zinc finger protein 40 that is encoded in the genome of mouse." [PRO:DNx, OMA:Q03172, PMID:15778499]
comment: Category=organism-gene.
synonym: "mHIVEP1" EXACT PRO-short-label [PRO:DNx]
synonym: "alpha A-CRYBP1 (mouse)" EXACT [UniProtKB:Q03172]
synonym: "alpha A-crystallin-binding protein 1 (mouse)" EXACT [UniProtKB:Q03172]
synonym: "alpha A-crystallin-binding protein I (mouse)" EXACT [UniProtKB:Q03172]
synonym: "transcription factor alphaA-CRYBP1 (mouse)" EXACT [UniProtKB:Q03172]
synonym: "Cryabp1" RELATED [UniProtKB:Q03172]
synonym: "Znf40" RELATED [UniProtKB:Q03172]
xref: UniProtKB:Q03172
intersection_of: PR:000008604 ! zinc finger protein 40
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
relationship: has_gene_template MGI:96100 ! Hivep1 (mouse)
relationship: has_canonical_sequence UniProtKB:Q03172 ! Q03172-1
[Term]
id: PR:D3YWT3
name: transcription factor 7-like 2 isoform D3YWT3 (mouse)
def: "A transcription factor 7-like 2 (mouse) that is a translation product of some mRNA giving rise to a protein with the amino acid sequence represented by UniProtKB:D3YWT3." [PRO:DNx, UniProtKB:D3YWT3, PMID:20044351]
comment: Category=organism-sequence.
synonym: "mTCF7L2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:D3YWT3
is_a: PR:Q924A0 ! transcription factor 7-like 2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus
[Term]
id: PR:A2AHT3
name: calsenilin isoform 3 sequence variant G41R (mouse)
def: "A calsenilin isoform 3 (mouse) that has an Arg residue at the position equivalent to Gly-41 of the amino acid sequence represented by UniProtKB:Q9QXT8-3. UniProtKB:Q9QXT8-3, Gly-41, CHEBI:29952." [PRO:DAN, PMID:11792319]
comment: Category=organism-sequence.
synonym: "mKCNIP3/iso:3/var:G41R" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9QXT8-3, Gly-41, CHEBI:29952" EXACT PRO-proteoform-std [PRO:DNx]
xref: UniProtKB:A2AHT3
is_a: PR:000036314 ! calsenilin (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus