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#651 annotation check mcb1

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2015-06-16
2015-06-02
No

I'm not sure why I made a not of this one now, but I wondered if mcb1 is definitely

GO detection of DNA damage stimulus involved in mitotic G2 DNA damage checkpoint
(this would make it a 'sensor' for the checkpoint)

rather than just causing a problem which results in activation of the checkpoint.

I think we only know that arrest requires that the chk1 checkpoint is functional

Thoughts?

Discussion

  • Midori Harris

    Midori Harris - 2015-06-02

    I haven't dealt directly with the paper cited for that annotation, but I don't know of any other reasons to prefer a GO annotation over just phenotypes for mcb1 and checkpoints.

     
  • Valerie Wood

    Valerie Wood - 2015-06-02

    Ah Ok, it was me!. I deleted the GO annotation but i 'll double check with Jacky.
    I have a not on my list to discuss phenotype vs. GO annotation with here so this will be a good example.

     
  • Midori Harris

    Midori Harris - 2015-06-16
    • Description has changed:

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     I'm not sure why I made a not of this one now, but I wondered if mcb1 is definitely 
    
    • assigned_to: Midori Harris --> Valerie Wood
     

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