PANET, a Cytoscape plugin is developed to efficiently analyze the robustness-related dynamics and feed-forward/feedback loop structures of biological networks. This is an advanced plugin of NetDS (http://netds.sourceforge.net/). We employed OpenCL library to make the time-consuming parts of NetDS are processed in parallel. Finally, in comparison to the original NetDS, PANET performed large-scale robustness calculation and feed-forward/feedback loop examination faster by several hundred times for a human signaling network with 1609 nodes and 5063 links.

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2013-12-13
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