ZDB-PUB-100427-14 The proepicardial organ (PE) contributes to the cellular diversity of the developing heart by giving rise to the epicardium as well as vascular smooth muscle cells and fibroblasts
See also ZDB-PUB-080218-16.
the epicardium, forms from a cluster of progenitor cells termed the proepicardium (PE). PE cells migrate onto the myocardium to give rise to the epicardium.PMID: 24885804
The proepicardium is a cluster of cardiac progenitor cells that develops adjacent to the heart and migrates onto the heart to form the outermost layer, the epicardium. Zebrafish form a PE on the pericardial wall, adjacent to the atrioventricular (AV) junction. We find that a PE cluster located at the AV junction forms a cellular bridge between the pericardial mesothelium and the heart. Additional PE clusters form near the venous pole, are released into the pericardial space, and subsequently attach to the heart.ZDB-PUB-140603-8
proepicardial organ a transient structure clusters of spherical cells clusters near sinus venosus, between the atrium and the yolk and near the atrioventricular junction,
primary term name proepicardial cluster.
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