#15 syncytium

[donghui]

Do we have a PO term 'syncytium' (I did not find it)? If not, should it be added to PO Plant Cell Type? The Cell Type Ontology ID for syncytium is CL:0000228. Please also refer to PMID 16942607.

Thanks!

Donghui

[Anonymous]

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syncytium is formed upon nematode infection to the host plants, is it present in the uninfected plant tissue?

[donghui]

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is it present in the uninfected plant tissue?

Here is one example: PMID 12421698. 'In Arabidopsis, as in many other species, the endosperm that nutures the embryo in the seed initially develops as a syncytium'.

[donghui]

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Another related example is 8-nucleate megagametophyte. Please refer to the following GO term:

cellularization of megagametophyte

http://www.godatabase.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0009558&session_id=3426b1171666428

[Pankaj Jaiswal]

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Hi,

Avoid the syncytium of the endosperm for now. That's a totally different situation.

As of now the two types of syncytium like cells that we can find cited by the Publication PMID 15053756
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15053756&query_hl=3&itool=pubmed_docsum
are "Giant Cell" and "syncytium cell". These are found in the root vascular cylinder/system.

Based on that we need two terms

Plant Cell PO:0009002
--isa--root giant cell PO:NEW
--isa--root syncytium cell PO:NEW

root vascular system PO:0003011
--partof--root giant cell PO:NEW
--partof--root syncytium cell PO:NEW

Details are

TERM: root giant cell
PO:NEW
DEFINITION: Multinucleate cell developed by a series of events involving kayokinesis but not cytokinesis of the initial feeding feeding cell. The events are induced by root knot nematodes (e.g. Meloidogyne sp.) entering the feeding cells (any cells) of the root vascular system. [ref: PMID 15053756]

TERM: root syncytium cell
PO:NEW
DEFINITION: Multinucleate cell developed by a series of events involving fusion with the neighboring dividing cells. The events are induced by cyst nematodes (e.g. Heterodera schachtii) entering the feeding cells (any cells) of the root vascular system. [ref: PMID 15053756]
COMMENT: Unlike PO_term root giant cell (PO:NEW) the process of formation of root syncytium cell does not involve karyokinesis.

let me know if it works. I have prefixed the terms names with 'root' because we know there is a syncytium term is used in endosperm formation. Perhaps we will addd the endosperm term later.

[Pankaj Jaiswal]

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added the terms to po_anatomy.obo ver 1.37

[Term]
id: PO:0005026
name: root giant cell
namespace: plant_structure
def: "Multinucleate cell developed by a series of events involving kayokinesis but not cytokinesis of the initial feeding feeding cell. The events are induced by root knot nematodes (e.g. Meloidogyne sp.) entering the feeding cells (any cells) of the root vascular system." [PMID:15053756, GR:pj]
subset: Arabidopsis
is_a: PO:0009002 ! plant cell
relationship: part_of PO:0003011 ! root vascular system

[Term]
id: PO:0005027
name: root syncytium cell
namespace: plant_structure
def: "Multinucleate cell developed by a series of events involving fusion with the neighboring dividing cells. The events are induced by cyst\nnematodes (e.g. Heterodera schachtii) entering the feeding cells (any cells) of the root vascular system." [PMID:15053756, GR:pj]
subset: Arabidopsis
is_a: PO:0009002 ! plant cell
relationship: part_of PO:0003011 ! root vascular system