#825 NTR: stained fixed slide specimens

[Chris Stoeckert]

These terms are needed for OBIB to aid investigators searching for specimens that have been stained by a particular method (H&E or immunohistochemistry). The proposed pattern is to define a staining process in order to define the desired specimens as the output of that process.

H&E slide staining: a staining process using hematoxylin and eosin. The staining is applied to fixed specimens on slides to observe the whole structure and morphology of cells in a tissue; nuclei are stained dark blue/purple while cytoplasm is stained pink.
Def. Source: http://www.histalim.com/accueil/activities/our-services/histology/hematoxylin-eosin-2/
Specified input: fixed tissue slide specimen
Specified output: H&E stained fixed tissue slide specimen.

H&E stained fixed tissue slide specimen: A fixed tissue slide specimen that is the output of H&E slide staining.

IHC slide staining: a staining process using labeled antibodies, i.e. the analytical part of immunohistochemistry. The staining is applied to fixed specimens on slides to identify biomarkers in tissues.
Def. Source: http://www.agilent.com/cs/library/technicaloverviews/public/08002_ihc_staining_methods.pdf
Specified input: fixed tissue slide specimen
Specified output: IHC stained fixed tissue slide specimen.

IHC stained fixed tissue slide specimen: A fixed tissue slide specimen that is the output of immunohistochemistry slide staining.
Alternate label: immunohistochemistry slide specimen

[Chris Stoeckert]

discussed on 12/12 call
suggestion is H&E-stained, IHC-stained

[Chris Stoeckert]

These have been added to OBI