NeoPipe - Protein family analysis

New advanced technologies including the next-generation DNA, and information technology have significantly improved our capacities of developing biological knowledge and changing our understanding of diseases, phenotype and genotype. In this post-genomic context, protein sequence analysis is a key issue to better understand the evolutionary, structural and functional aspects.

NeoPipe is a tool of analyzing a protein family , which consists of 8 steps concerning the search for homologous sequences in multiple databases (protein, 3D structures,…) and functional and structural annotations of clustered multiple alignment of complete sequences (MACS). Those indicate the relationship between the protein subfamilies. .The emphasis is to get a high quality alignment by performing refinement and corrections (evaluated by a quality score at each steps) and giving a clustered and annotated alignment of potential subgroups