Running this document with lualatex
\documentclass{article}
\usepackage{luatex85}
\usepackage{tikz}
\begin{document}
bl
\end{document}
gives the error
! Package pgf Error: Driver file ``pgfsys-luatex.def'' not found..
This is due to a missing file in pgf. https://sourceforge.net/p/pgf/bugs/384/
The bug hasn't been resolved on the package side, but in texlive the file has been added to tex/generic/pgf/systemlayer/ with the agreement of Till Tantau. See https://www.tug.org/svn/texlive/trunk/Master/texmf-dist/tex/generic/pgf/systemlayer/
I suggest to add it to pgf in MiKTeX too.
