Since the last update running fc-cache or a small xelatex document like this
\documentclass[]{article}
\usepackage{fontspec}
\begin{document}
MWE
\end{document}
leads to a number of messages in the terminal
~~~~~~
Unable to update the static FcBlanks: 0x0600
Unable to update the static FcBlanks: 0x0601
Unable to update the static FcBlanks: 0x0602
Unable to update the static FcBlanks: 0x0603
Unable to update the static FcBlanks: 0x06dd
Unable to update the static FcBlanks: 0x070f
Unable to update the static FcBlanks: 0x2028
Unable to update the static FcBlanks: 0x2029
Unable to update the static FcBlanks: 0xfff9
Unable to update the static FcBlanks: 0xfffa
Unable to update the static FcBlanks: 0xfffb
~~~~~~~
I suspect that the <blank> settings in fonts.conf.in / fonts.conf is reponsable as the newest fontconfig no longer accept this entries. See e.g. http://comments.gmane.org/gmane.comp.fonts.fontconfig/5495 and https://github.com/behdad/fontconfig/blob/master/fonts.conf.in
(I couldn't test what happens if one remove this section as I don't know how to recreate fonts.conf after a change of fonts.conf.in.)
This has been fixed.