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#89 Cell Viability

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2
2015-07-04
2015-06-01
Todd Kveton
No

We need to make a term that express that a gene product is essential for viability and a term for synthetic lethals.

Discussion

  • Todd Kveton

    Todd Kveton - 2015-06-02

    Suggested parent term OMP:0000174 growth phenotype
    New Child term: cell viability phenotype
    Definition: A viability phenotype where the trait in question is the ability of the cell or cells to survive.

    New Child term(parent being cell viability phenotype): essential for viability phenotype
    Definition: A phenotype where the single gene in question is essential for the viability of the cell

    New Child term(parent being cell viability phenotype): synthetic lethal phenotype
    Definition: A phenotype where the genes in question are essential for the viability of the cell

     

    Last edit: Debby Siegele 2015-07-04
  • Todd Kveton

    Todd Kveton - 2015-06-02

    Make parent term OMP:0000000 microbial phenotype? Just give cell viability its own category.

     
  • Debby Siegele

    Debby Siegele - 2015-06-03

    drafts:

    parent: altered viability phenotype Def. A microbial phenotype that describes a change in the ability of a cell or cells to survive and/or reproduce.

    children:
    decreased viability
    abolished viability (syn. nonviable or non-viable)
    increased viability

    child term: nonviable phenotype A viability phenotype where a mutation or environmental condition prevents growth and/or reproduction of a cell or cells.

     

    Last edit: Debby Siegele 2015-06-03
  • Debby Siegele

    Debby Siegele - 2015-07-04

    How FYPO handles viability.

    FYPO:0000049 ! inviable cell
    synonyms: essential, lethal
    def: A viability phenotype in which a cell is unable to survive under conditions in which wild type cells survive.

     

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