An update for Mendel's Accountant, v1.4.1 has just been released. This requires that v1.2.1 already be installed. v1.4.1 has a much improved user interface and simulation monitoring capabilities. Moreover, there are numerous improvements and bug fixes in the Mendel simulation engine, with additional capabilities for predicting the selection threshold both for deleterious and beneficial mutations.
Mendel's Accountant, a numerical simulation program to track genetic changes over time, version 1.2 for Windows was recently released. This version includes numerous improvements over the previous 1.0 release, which are enumerated as follows:
(1) added selection threshold treatment,
(2) implemented heap sort algorithm in place of quick sort algorithm,
(3) improved treatment of synergistic epistasis,
(4) improved output diagnostics,
(5) improved handling of favorable mutations
Mendel 1.0.1 was officially released on May 22, 2007. It will be publicly presented at the 2007 International Conference on Computational Sciences May 29, 2007, at the Graduate University of the Chinese Academy of the Sciences, with the paper titled "Using Computer Simulation to Understand Mutation Accumulation Dynamics and Genetic Load" by Sanford et al. Additionally, it will appear online June 2007 at the online Journal of Scalable Computing www.scpe.org with the paper titled "Mendel's Accountant: a biologically realistic forward-time population genetics program" by Sanford et al.