[Mauve-users] Unexpected alignment result
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From: Christine J. <chr...@gm...> - 2017-06-15 15:24:17
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Hey there, I aligned two Tuberculosis genomes with progressiveMauve with default paramaters and got a puzzling result. (see below -I did not include the sequence of the first block, as it is very long and not part of the problem) I expect the sequences of the second and the last block to be aligned in one single block as their sequences are almost the same... What could be the reason for such a behaviour? Thanks a lot, Christine #FormatVersion Mauve1 #Sequence1File GCF_000153685.2_ASM15368v2_genomic.fna #Sequence1Format FastA #Sequence2File GCF_001545055.1_ASM154505v1_genomic.fna #Sequence2Format FastA > 1:103-4408223 + GCF_000153685.2_ASM15368v2_genomic.fna .... > 2:2-4426387 + GCF_001545055.1_ASM154505v1_genomic.fna ... = > 1:1-102 + GCF_000153685.2_ASM15368v2_genomic.fna TTTGTGGATAGCCATGTGGACAGTTCACCTGCCCACAACAACGGTTGTAGCTCGACCCGGAACCAAGACCCGGAACTAACGAGAACCAGGGAGATACGTCGT = > 1:4408224-4408224 + GCF_000153685.2_ASM15368v2_genomic.fna A = > 2:1-1 + GCF_001545055.1_ASM154505v1_genomic.fna T = > 2:4426388-4426489 + GCF_001545055.1_ASM154505v1_genomic.fna ATTTGTGGATAGCCATGTGGACAGTTCACCTGCCCACAACAACGGTTGTAGCTCGACCCGGAACCAAGACCCGGAACTAACGAGAACCAGGGAGATACGTCG |