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Filter by AF value

Elena
2014-05-22
2014-05-23
  • Elena

    Elena - 2014-05-22

    Dear Andreas,
    I have been using Lofreq with a set of data from bacteria to identify low frequence SNP that explain microevolution. I wanted to filter by AF lower than 95% and above 75% to generate a smaller file to work with. There is any way I can do it with lofreq call?
    Thanks,

    Elena

     
    • Andreas Wilm

      Andreas Wilm - 2014-05-22

      Hi Elena,

      filtering is a separate downstream step. You will have to run 'lofreq
      filter' with '--af-min 0.75 --af-max 0.95' to apply the mentioned
      allele frequency filtering criteria.

      For older versions (i.e. <2) you would use 'lofreq_filter.py
      --min-freq' but there's no direct equivalent for maximum allele
      frequency.

      Hope this helps,
      Andreas

      On 22 May 2014 14:16, Elena marulin@users.sf.net wrote:

      Dear Andreas,
      I have been using Lofreq with a set of data from bacteria to identify low
      frequence SNP that explain microevolution. I wanted to filter by AF lower
      than 95% and above 75% to generate a smaller file to work with. There is any
      way I can do it with lofreq call?
      Thanks,

      Elena


      Filter by AF value


      Sent from sourceforge.net because you indicated interest in
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      --
      Andreas Wilm
      andreas.wilm@gmail.com | mail@andreas-wilm.com | 0x7C68FBCC

       
      • Elena

        Elena - 2014-05-23

        Hi Andrea,

        It have the beta version and was not working but I download the last
        version of lofreq and it works perfectly.
        Thanks also for improving the information in the help file.

        Kindly,

        Elena

        2014-05-22 20:04 GMT+10:00 Andreas Wilm onde@users.sf.net:

        Hi Elena,

        filtering is a separate downstream step. You will have to run 'lofreq
        filter' with '--af-min 0.75 --af-max 0.95' to apply the mentioned
        allele frequency filtering criteria.

        For older versions (i.e. <2) you would use 'lofreq_filter.py
        --min-freq' but there's no direct equivalent for maximum allele
        frequency.

        Hope this helps,
        Andreas

        On 22 May 2014 14:16, Elena marulin@users.sf.net wrote:

        Dear Andreas,
        I have been using Lofreq with a set of data from bacteria to identify low
        frequence SNP that explain microevolution. I wanted to filter by AF lower
        than 95% and above 75% to generate a smaller file to work with. There is
        any
        way I can do it with lofreq call?
        Thanks,

        Elena

        Filter by AF value

        Sent from sourceforge.net because you indicated interest in
        https://sourceforge.net/p/lofreq/discussion/general/

        To unsubscribe from further messages, please visit
        https://sourceforge.net/auth/subscriptions/

        --
        Andreas Wilm
        andreas.wilm@gmail.com | mail@andreas-wilm.com | 0x7C68FBCC


        Filter by AF valuehttp://sourceforge.net/p/lofreq/discussion/general/thread/ec8a1426/?limit=25#9091/fd60

        Sent from sourceforge.net because you indicated interest in
        https://sourceforge.net/p/lofreq/discussion/general/

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        https://sourceforge.net/auth/subscriptions/

         
        • Andreas Wilm

          Andreas Wilm - 2014-05-23

          Hi Elena,

          I just noticeda few more tiny errors in the usage information and
          fixed them. Do let me know if you have any ideas for improvement or
          find flaws.

          Thanks and good luck with your analysis,
          Andreas

          On 23 May 2014 08:35, Elena marulin@users.sf.net wrote:

          Hi Andrea,

          It have the beta version and was not working but I download the last
          version of lofreq and it works perfectly.
          Thanks also for improving the information in the help file.

          Kindly,

          Elena

          2014-05-22 20:04 GMT+10:00 Andreas Wilm onde@users.sf.net:

          Hi Elena,

          filtering is a separate downstream step. You will have to run 'lofreq
          filter' with '--af-min 0.75 --af-max 0.95' to apply the mentioned
          allele frequency filtering criteria.

          For older versions (i.e. <2) you would use 'lofreq_filter.py
          --min-freq' but there's no direct equivalent for maximum allele
          frequency.

          Hope this helps,
          Andreas

          On 22 May 2014 14:16, Elena marulin@users.sf.net wrote:

          Dear Andreas,
          I have been using Lofreq with a set of data from bacteria to identify low
          frequence SNP that explain microevolution. I wanted to filter by AF lower
          than 95% and above 75% to generate a smaller file to work with. There is
          any
          way I can do it with lofreq call?
          Thanks,

          Elena

          Filter by AF value

          Sent from sourceforge.net because you indicated interest in
          https://sourceforge.net/p/lofreq/discussion/general/

          To unsubscribe from further messages, please visit
          https://sourceforge.net/auth/subscriptions/

          --
          Andreas Wilm
          andreas.wilm@gmail.com | mail@andreas-wilm.com | 0x7C68FBCC


          Filter by AF
          valuehttp://sourceforge.net/p/lofreq/discussion/general/thread/ec8a1426/?limit=25#9091/fd60

          Sent from sourceforge.net because you indicated interest in
          https://sourceforge.net/p/lofreq/discussion/general/

          To unsubscribe from further messages, please visit
          https://sourceforge.net/auth/subscriptions/


          Filter by AF value


          Sent from sourceforge.net because you indicated interest in
          https://sourceforge.net/p/lofreq/discussion/general/

          To unsubscribe from further messages, please visit
          https://sourceforge.net/auth/subscriptions/

          --
          Andreas Wilm
          andreas.wilm@gmail.com | mail@andreas-wilm.com | 0x7C68FBCC

           

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