Users rejoice: we've just released LoFreq 2.1!
The most important changes are the following:
- LoFreq can now call indels. Indel calling depends on a good alignment (use BWA-MEM and refine with lofreq viterbi
), indel qualities (use lofreq indelqual
or GATK's BQSR) and indel alignment qualities (computed internally). The feature is off by default, because it's still considered a bit suboptimal. To enable it, use --call-indels
as extra argument for lofreq call
and lofreq somatic
.
somatic
is now bgzipped)This release comes as a binary package for Linux and MacOSX and now also with MIT-licensed source-code. Please have a look at the files section.
Usage has changed slightly, but should be obvious from the commandline help of LoFreq's subcommands. We will be updating the online documentation soon after we've moved source code and website to github and github-pages (will be announced here) so check back soon!
Andreas