LoDel

LoDel is a Java based somatic deletion caller designed for whole-genome sequencing data from unmatched samples. LoDel is specialized for identifying somatic deletions with frequently existing sampling issues : low mutational frequency in cell population and absence of the matched control samples.
The important features of LoDel are:

•Estimation of accurate mutation frequency in a mixed disease sample
•Improved somatic deletion calling based on the probabilistic model with the parameter estimation