Can someone please explain to me the problem here?

1) How would ASIO help if a keyboard is NOT even in the equation?

It's more of something to get used to. When you play on the keyboard (computer; QWERTY), you expect a visual feedback so you know which note is being played. However, it's just a matter of not depending on that; use the ears more! Anyway I use the mouse all the time..Maybe play some FPS games and season up? =P