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What versions of the iscsi initiator are you using? If you are using a FC rpm do "rpm -q iscsi-initiator-utils".

There has been a problem with open-iscsi and tape, because the tape driver assumes the initiator supports clustering and the initiator does not. In the upstream kernel this is fixed though. For FC5, if you update to the current FC kernel (I think it is 2.6.18 or .19 based) this should be fixed.

For linux-iscsi, I am not sure if it supported tape. There had been several bug reports for a similar reason. Do you see a oops trace in /var/log/messages?