Hi Shea,

I'm doing genotype-phenotype association with the 'core_SNPs_matrix.fasta' file of 200 bacterial genomes.

I had not significant result with 15.000 core SNPs and I think the phenotype is not explained in the core genome. However, in order to definitely accept this hypothesis, I would like the obtain the highest possible number of core SNPs.

I'm not thinking in designing microarray probes, if this could help.

If you know how to achieve this with your program I would be grateful.

Thank so much.
All the best,
Bernardo