Currently, most of the Rhea reactions assigned to an enzyme entry have undefined direction (UN).
It has been requested that, except for other cases where a concrete direction is assigned, this must be changed to use the bidirectional reaction (BI).
Once the Rhea reactions have been normalised - very very soon -, i.e. they share all of their attributes except for Rhea ID, direction and cross-references, this change of assignment will be done programatically.
It must be emphasised, even so evident it may seem, that UN means "LR or RL or BI" while BI means "LR and RL". Thus, enzymes will have assigned a reaction which occurs in both directions at the same time.
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