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functional connectivity DMN help

2017-08-03
2017-08-03
  • Bartosz Bohaterewicz

    Dear Experts,

    I would like to perform functional connectivity analysis within DMN of resting state datas from 2 groups. After preprocessing and band-pass filtering. I'm going to perform ICA and select the components having higest correlation within DMN (template from gift), and compared them between groups using two sample t-test in SPM with FDR.

    Please let me know if my understanding is correct, or should i use MANCONVIAN to perform FC and comparison between groups.

    I'll be grateful for any help.

     
    • Srinivas Rachakonda

      Hi,

      You could identify the DMN component and compare across groups using two
      sample t-test (SPM stats) or use mancovan and select features.

      Thanks,
      Srinivas

      On Wed, Aug 2, 2017 at 6:50 PM, Bartosz Bohaterewicz andywil@users.sf.net
      wrote:

      Dear Experts,

      I would like to perform functional connectivity analysis within DMN of
      resting state datas from 2 groups. After preprocessing and band-pass
      filtering. I'm going to perform ICA and select the components having higest
      correlation within DMN (template from gift), and compared them between
      groups using two sample t-test in SPM with FDR.

      Please let me know if my understanding is correct, or should i use
      MANCONVIAN to perform FC and comparison between groups.

      I'll be grateful for any help.

      functional connectivity DMN help
      https://sourceforge.net/p/icatb/discussion/309910/thread/4f971183/?limit=25#21df


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      • Bartosz Bohaterewicz

        Thank you for reply.

        In conclusion:
        to perform FC within DMN: should I perform ICA on both groups, select components with highest DMN correlations usting "remove components" feature, and compare both groups using gift output files by SPM 2-nd level analysis?

        All the best

         
  • Bartosz Bohaterewicz

    Therefore should I use "sort components" and then choose DMN mask" or feed DMN mask in "setupICA Defaults"?

     
  • Shania

    Shania - 2017-11-14

    Hi,
    I have made a query regarding group analysis in GIFT toolbox. https://sourceforge.net/p/icatb/discussion/309910/thread/374a0b23/#8590
    Further to the question, we have identified resting state networks for individual components and have to perform group analysis using two sample t-test in SPM. After group analysis in gift toolbox we got the file named as 'test03.fastica_ica_parameter_info'. We visualised all the components from the mean image. We want to analyse the difference in DMN connectivity between patients and controls. Please tell us which of the input files can be incorporated to create a GLM in the SPM second level analysis.
    Thanks in advance.

     

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