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From: davila <da...@io...> - 2005-01-26 20:27:30
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Hi Aaron, Mike, Indeed, comparative genomics will receive major benefit from = phylogeny/evolutionary analyses...=20 Could you share any further info/details on your CDAT initiative ?... = sure, tables should support (help to differentiate) gene trees from = species trees, (phylogenomics ?) etc. I hope to be able to provide a draft schema for this next week or so, = hope it is not too late...=20 Cheers, Alberto -----Original Message----- From: Aaron J. Mackey [mailto:am...@pc...] Sent: Wed 1/26/2005 2:22 PM To: gusdev-gusdev Cc:=09 Subject: Re: [Gusdev-gusdev] GUS 3.5 Release On Jan 26, 2005, at 11:13 AM, Michael Saffitz wrote: > GUS doesn't currently support phylogeny/evolutionary data, but are=20 > very open to adding it to GUS. Do you have a schema (rough or=20 > otherwise) in mind? I think the upcoming comparative genomics efforts here (and elsewhere)=20 will certainly require support for evolutionary analyses. I would=20 encourage those doing the schema design to consider both multiple=20 sequence alignments and trees (including associated bootstraps,=20 likelihood, branch lengths, etc) as experimental results that may be=20 computed in many different fashions. I.e. don't fall into the trap of=20 the "one true tree", because it doesn't exist. I'd be very interested to be involved in this effort, and to give a=20 talk on my own phylogenetic sequence database (CDAT) for consideration=20 as one possible schema to mimic. -Aaron -- Aaron J. Mackey, Ph.D. Dept. of Biology, Goddard 212 University of Pennsylvania email: am...@pc... 415 S. University Avenue office: 215-898-1205 Philadelphia, PA 19104-6017 fax: 215-746-6697 |