Re: [Gusdev-gusdev] GUS 3.5 Release

[Aaron J. M. <am...@pc...>]

On Jan 26, 2005, at 11:13 AM, Michael Saffitz wrote:

> GUS doesn't currently support phylogeny/evolutionary data, but are 
> very open to adding it to GUS.  Do you have a schema (rough or 
> otherwise) in mind?

I think the upcoming comparative genomics efforts here (and elsewhere) 
will certainly require support for evolutionary analyses.  I would 
encourage those doing the schema design to consider both multiple 
sequence alignments and trees (including associated bootstraps, 
likelihood, branch lengths, etc) as experimental results that may be 
computed in many different fashions.  I.e. don't fall into the trap of 
the "one true tree", because it doesn't exist.

I'd be very interested to be involved in this effort, and to give a 
talk on my own phylogenetic sequence database (CDAT) for consideration 
as one possible schema to mimic.

-Aaron

--
Aaron J. Mackey, Ph.D.
Dept. of Biology, Goddard 212
University of Pennsylvania       email:  am...@pc...
415 S. University Avenue         office: 215-898-1205
Philadelphia, PA  19104-6017     fax:    215-746-6697