The Guido web site at http://guido.sf.net/ now has some user documentation as well as programmer documentation.
Also, I've been working for the last several weeks on an installer for Guido that will hopefully ease some of the installation pains on all platforms, but particularly Win32. When the installer is released, hopefully tonight or tomorrow, I'll put a link to it on the web site, as well as some instructions on how to use it. The installer will also be a separate release from the main Guido package itself, since it's not really part of the application.
I've made several key bug fixes as well, which should hopefully get most everyone working after the installation. There are still several big issues to be resolved, and whatever you find wrong in the new release can be logged at http://www.sf.net/projects/guido/ in the Bugs section.
If you have trouble installing, please log a help request at that same location in the Support section. I'll do my best to help you.