From: Leonore R. <lr...@ac...> - 2004-10-15 22:11:42
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Ok here is something of a wish list- I've asterisked ones that at a minimum should be there since of course, what we know/ can show depends upon the available data. I concur with Stacia that all assertions should be supported with tracable evidence/methodologies. I also dont mean to imply that every MOD should physically store all of the information presented here. For example, TAIR does not store information/alignments for homology but does link to this information in other databases. But if the information is available...be nice to find. I wonder if it helps to distinguish between minimal information for a SEQUENCED locus vs. GENETICALLY defined. For now- Ill assume were are talking about sequenced genes and not single recessive mutants or QTLs. -Leonore Reiser Locus Info* Systematic Locus Identifier* Gene Name* Gene Alias(es)* Gene Model Type (e.g. protein coding, miRNA, unknown...etc.)* Physical/Genetic Linkage Map Location (chromosome, coordinates)* Summary/Brief Description* Annotated Sequence (gene features annotated + EVIDENCE* that is -is the structure experimentally verified or predicted and what is the evidence) History Function/Biological Role/Expression/Localization GO Annotations Gene Expression Data (Microarray, EST, SAGE, MPSS, in-situ, etc..) (supra- cellular) Localization (immunohistochemistry, GFP/YFP) Alleles and Phenotypes Sequence Variation (nt sequence [C->A at 2344 bp] and coding sequence change[ e.g.nonsense mutation at AA 467]) Variation Type:(e.g. insertion, deletion, etc..) Mutagen: e.g. EMS, RNAi et... Type: e.g. hypermorph, neomorph,etc.. Phenotype Pathways and Interactions Genetic Pathways Metabolic Pathways Signaling Pathways Interacting Partners (binds to DNA/binds to Protein/modifies X) Protein * Sequence* Domains/Motifs* Post-translational modifications Tryptic Digest Patterns pI* Molecular Weight* Homologies* Reagents Clones Antibodies Strains (e.g. seed stocks) Literature ------------------------------------------------------------------------------- Leonore Reiser, Ph.D. lr...@ac... The Arabidopsis Information Resource FAX: (650) 325-6857 Carnegie Institution of Washington Tel: (650) 325-1521 ext. 311 Department of Plant Biology URL: http://arabidopsis.org/ 260 Panama St. Stanford, CA 94305 ------------------------------------------------------------------------------- |