GETTING STARTED
Web interface
GEPETTO web page
The SM2PH-Central website integrates [GEPETTO]. It can be accessed either directly or through the menu bar :

This leads us to the gene prioritization web page which is pretty simple :
There are 5 components :

- The training set as a gene symbols (or Uniprot accessions) list
- The test set as a gene symbols (or Uniprot accessions) list
- The list of [GEPETTO] modules that will be used (if checked)
- The button to run prioritization
- The reset button that reinitializes the page with default parameters (clear set fields and checked all boxes).
How to use it?
Use [GEPETTO] is very easy :
- Provide the training set
- Provide the test set
- Select data sources that will be used ([GEPETTO] modules)
- Click on the Prioritize button to start the prioritization
Currently, when the prioritization is done, [GEPETTO] return results like this :


The first results are provided by local prioritization from all modules. At the end, there is the overall result from global prioritization.
Reminder : the identifier of genes must be characterized by gene symbols.
You can also set up the training set from a KEGG Pathway :

or from serach results using full text :

using the
button.
Command line
Warning : Only GNU/Linux operating system (OS) based on Debian or Red Hat Enterprise Linux can support [GEPETTO] due to dependencies.
Downloads
All releases can be downloaded from SourceForge. Select the version you want to download and select the distribution you want to :
- installer-full : containing all (sources, data, modules,...)
Sources
License
The [GEPETTO] code itself is using the LGPL-2.1 License.
Some other components we integrate with have their own license :
- BLAST is a "United States Government Work" under the terms of the United States Copyright Act.
- R as a package is licensed under GPL-2 | GPL-3.
- RJava as a package is licensed under GPL-2.
- Spring Framework is licensed under Apache License
- jBPM is licensed under GNU LGPL
- Apache Commons liraries is licensed under Apache License
For all the Java libraries, please check it individually.
Source code
[GEPETTO] now uses SVN for its source code version control system. The sources of the [GEPETTO] project can be founded here :
- svn+ssh://svn.code.sf.net/p/gepetto/code/GEPETTO
- svn+ssh://svn.code.sf.net/p/gepetto/code/GEPETTOModel
The source of local prioritization modules we integrate with can be found here :
- svn+ssh://svn.code.sf.net/p/gepetto/code/Alignment
- svn+ssh://svn.code.sf.net/p/gepetto/code/Evolucode
- svn+ssh://svn.code.sf.net/p/gepetto/code/Geco
- svn+ssh://svn.code.sf.net/p/gepetto/code/GxDb
- svn+ssh://svn.code.sf.net/p/gepetto/code/IDGP
- svn+ssh://svn.code.sf.net/p/gepetto/code/Pubmed
- svn+ssh://svn.code.sf.net/p/gepetto/code/String