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From: Reinhard H. <rho...@in...> - 2001-04-04 15:10:56
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Hi there! I have not yet installed GeneX, but will probably be using it later this year. However, during a brief overview of the GeneX features, it appears as though there are only two ways to detect (statitically valid) differentially expressed genes: via t-test with bonferroni correction and a bayesian modeller. I think two additional features would be extremely helpful: 1. Implementation of an ANOVA-like routine that identifies differentially expressed genes in, for example, developmental studies where no baseline condition can be defined, and that contains >3 conditions with a number of replicates; 2. Inplementation of non-parametric tests like Kruskal-Wallis, also in conjunction with 1. Please let me know what you think of these points. Greetings Dr. Reinhard Hoffmann Basel Institute for Immunology Grenzacherstr. 487 4005 Basel Switzerland Fon +4161-6051425 Fax +4161-6051364 email rho...@in... |