#11666 rel between "axonemal dynein complex" and "cytoplasmic dynein complex"

[Karen Christie]

Hi,

It looks quite odd to me that "axonemal dynein complex" is_a "cytoplasmic dynein complex".

I see that the term "axoneme part" is_a "cytoplasmic part", and perhaps this is part of the reason.

However, the people who study dyneins would not consider an axonemal dynein to be a cytoplasmic dynein. Phylogenetic trees of dyneins separate into three groups:
- cytoplasmic dyneins (the "regular" one(s) that move on cytoplasmic MTs
- axonemal inner arm dyneins
- axonemal outer arm dyneins

So, maybe we could give "axonemal dynein complex" direct parentage under "dynein complex" GO:0030286

Maybe we don't need the "axoneme part" is_a "cytoplasmic part" relationship either, since teh axoneme is part of the cilium, which is separate from the cytoplasm.

thanks,

-Karen

[Paola Roncaglia]

(Hi David OS, I'm taking this one as it's cilia-related)

[Helen Attrill]

Hi,

Any up date on this? I have the same issues as Karen i.e. I want to distinguish between cytoplasmic and axonemal dynein complexes.

Thanks,
Helen