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#11471 NTR: endoribonuclease activity, cleaving miRNA-paired mRNA

BHF-UCL
closed-accepted
5
2015-01-22
2015-01-19
No

NTR: 'endoribonuclease activity, cleaving miRNA-paired mRNA’
Def: Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA, yielding 5'-phosphomonoesters.

as an equivalent to GO:0070551 endoribonuclease activity, cleaving siRNA-paired mRNA.

PMID:15260970

Please add db_xrefs GOC:BHF_miRNA and GOC:rph.

Thanks,
Rachael.

Discussion

  • Tanya Berardini

    Tanya Berardini - 2015-01-21
    • labels: miRNA --> miRNA, New term request
    • assigned_to: Tanya Berardini
     
  • Tanya Berardini

    Tanya Berardini - 2015-01-22
    • status: open --> closed-accepted
     
  • Tanya Berardini

    Tanya Berardini - 2015-01-22

    Added:

    [Term]
    +id: GO:0090624
    +name: endoribonuclease activity, cleaving miRNA-paired mRNA
    +namespace: molecular_function
    +def: "Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA, yielding 5'-phosphomonoesters." [GOC:BHF_miRNA, GOC:rph, PMID:15260970]
    +is_a: GO:0016891 ! endoribonuclease activity, producing 5'-phosphomonoesters

     

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