#11357 NTR:intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity

[Helen Attrill]

Hi,

A (long)-new-term request

"intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity"

(Catalysis of the transmembrane transfer of cation by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts.)

To sit under: intracellular ligand-gated ion channel activity GO:0005217
To annotate: D.mel Trpml, PMID:24375408 (Drosophila TRPML forms PI(3,5)P2-activated cation channels in both endolysosomes and plasma membrane.)

Thanks,

Helen

[Paola Roncaglia]

Hi Helen,

Sorry to keep you waiting. I'm afraid this will have to wait until next week as I'll be on leave for a few days. Thanks!

Paola

[Paola Roncaglia]

Hi Helen,

Thanks for waiting - here's your new term:

id: GO:0097682
name: intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity
namespace: molecular_function
def: "Catalysis of the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts." [GOC:ha, PMID:24375408]
is_a: GO:0005217 ! intracellular ligand-gated ion channel activity
is_a: GO:0005261 ! cation channel activity

(I added the cation channel activity parent)

Thanks and happy holidays!

Paola

[Helen Attrill]

Thanks!

Happy Christmas to you and all at the office.

Helen

On 17 Dec 2014, at 16:56, Paola Roncaglia wrote:

Hi Helen,

Thanks for waiting - here's your new term:

id: GO:0097682
name: intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity
namespace: molecular_function
def: "Catalysis of the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts." [GOC:ha, PMID:24375408]
is_a: GO:0005217 ! intracellular ligand-gated ion channel activity
is_a: GO:0005261 ! cation channel activity

(I added the cation channel activity parent)

Thanks and happy holidays!

Paola

[ontology-requests:#11357] NTR:intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity

Status: open
Group: FlyBase
Labels: New term request
Created: Thu Nov 27, 2014 05:14 PM UTC by Helen Attrill
Last Updated: Wed Dec 03, 2014 05:00 PM UTC
Owner: Paola Roncaglia

Hi,

A (long)-new-term request

"intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity"

(Catalysis of the transmembrane transfer of cation by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts.)

To sit under: intracellular ligand-gated ion channel activity GO:0005217
To annotate: D.mel Trpml, PMID:24375408 (Drosophila TRPML forms PI(3,5)P2-activated cation channels in both endolysosomes and plasma membrane.)

Thanks,

Helen

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