[DEPRECATED] Gene Ontology / Ontology requests / #11134 NTR: Vps4-Vta1 Complex

Jane Lomax - 2014-09-09

labels: --> protein complex

Description has changed:

Diff:

--- old +++ new @@ -1,4 +1,3 @@ - Hi, Could I please request a term for the Vps4-Vta1 Complex? Vps4-Vta1 Complex

assigned_to: Jane Lomax
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Jane Lomax - 2015-01-26

assigned_to: Jane Lomax --> Paola Roncaglia
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Paola Roncaglia - 2015-01-27

labels: protein complex --> protein complex, New term request
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Paola Roncaglia - 2015-01-27

Hi Helen,

Thanks for waiting! I'd add your requested term as follows, please let me know if you disagree with any of it:

GO:NEW Vps4-Vta1 complex
is_a protein complex
part_of GO:0010008 endosome membrane
capable_of_part_of GO:0070676 intralumenal vesicle formation
A protein complex involved in ESCRT-mediated intralumenal vesicle formation. The complex catalyzes disassembly of the ESCRT-III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT-III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1.
GOC:ha, PMID:20653365, PMID:20696398, PMID:25164817
Synonyms: Vta1-Vps4 complex (exact), Vps4 complex (broad)

Thanks,

Paola

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- Helen Attrill - 2015-01-29
  
  Thanks, Paola. It's all lovely!
  
  Regards,
  
  Helen
  
  On 27 Jan 2015, at 12:04, Paola Roncaglia wrote:
  
  Hi Helen,
  
  Thanks for waiting! I'd add your requested term as follows, please let me know if you disagree with any of it:
  
  GO:NEW Vps4-Vta1 complex
  is_a protein complex
  part_of GO:0010008 endosome membrane
  capable_of_part_of GO:0070676 intralumenal vesicle formation
  A protein complex involved in ESCRT-mediated intralumenal vesicle formation. The complex catalyzes disassembly of the ESCRT-III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT-III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1.
  GOC:ha, PMID:20653365, PMID:20696398, PMID:25164817
  Synonyms: Vta1-Vps4 complex (exact), Vps4 complex (broad)
  
  Thanks,
  
  Paola
  
  [ontology-requests:#11134] NTR: Vps4-Vta1 Complex
  
  Status: open
  Group: None
  Labels: protein complex New term request
  Created: Mon Sep 08, 2014 07:09 AM UTC by Helen Attrill
  Last Updated: Tue Jan 27, 2015 10:31 AM UTC
  Owner: Paola Roncaglia
  
  Hi, Could I please request a term for the Vps4-Vta1 Complex?
  
  Vps4-Vta1 Complex
  
  Synonyms: Vta1-Vps4 Complex, Vps4 Complex
  
  Def: The Vps4-Vta1 Complex is an oligomeric assembly of the AAA-ATPase Vps4 and its cofactor Vta1 and is involved in ESCRT-mediated intralumenal vesicle formation. The complex catalyzes disassembly of the ESCRT-III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT-III components back to the cytosol.
  
  Refs: PMID:20653365 (The ESCRT complexes. 2010)
  PMID:20696398 (Structural role of the Vps4-Vta1 interface in ESCRT-III recycling. 2010)
  PMID:25164817 (Vps4 Stimulatory Element (VSE) of the Cofactor Vta1 Contacts the ATPase Vps4 α7 and α9 to Stimulate ATP Hydrolysis.)
  
  Thanks
  
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  Related
  
  Ontology requests: ~~#11134~~
  
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Paola Roncaglia - 2015-01-29

Thanks Helen.

Here’s your term below. Should you need similar ones in the future, you could submit them via TG freeform (which has a field for capable_of_part_of process links). There’s also a regular TG template for protein complexes that have a capable_of function link. I was happy to add this one for you as you’d already waited some time, so no prob!
Any question on TG, please feel free to ask. Have a good day,

Paola

[Term]
id: GO:1990621
name: Vps4-Vta1 complex
namespace: cellular_component
def: "A protein complex involved in ESCRT-mediated intralumenal vesicle formation. The complex catalyzes disassembly of the ESCRT-III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT-III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1." [GOC:ha, PMID:20653365, PMID:20696398, PMID:25164817]
synonym: "Vps4 complex" BROAD []
synonym: "Vta1-Vps4 complex" EXACT []
is_a: GO:0043234 ! protein complex
relationship: capable_of_part_of GO:0070676 ! intralumenal vesicle formation
relationship: part_of GO:0010008 ! endosome membrane
created_by: pr
creation_date: 2015-01-29T10:02:30Z

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Paola Roncaglia - 2015-01-29

labels: protein complex, New term request --> protein complex, New term request, TG

status: open --> closed-accepted

Group: None --> FlyBase
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NTR: Vps4-Vta1 Complex

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#11134 NTR: Vps4-Vta1 Complex

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