Menu

#10768 OTR:GO:0043093 ! cytokinesis by binary fission

None
closed-fixed
None
5
2014-08-22
2014-04-09
Jim Hu
No

This term seems problematic, at minimum the term name is too generic for the definition.

Discussion

  • David Hill

    David Hill - 2014-04-10
    • assigned_to: David Hill
     
  • David Hill

    David Hill - 2014-05-09

    Based on the cited reference (PMID:12626683) how about this as a modified def:

    A cytokinesis process that results in the division of the cytoplasm and cell envelope of a cell into two daughter cells. Division of the cell envelope includes the division of all of the envelope layers including the plasma membrane.

     
  • Jim Hu

    Jim Hu - 2014-05-09

    Hi David,

    I should have left a more informative original comment. Did you also look at the parent?

    GO:0000910 ! cytokinesis
    def: "The division of the cytoplasm and the plasma membrane of a cell and its separation into two daughter cells." [GOC:mtg_cell_cycle]
    comment: Note that when annotating eukaryotic species, mitotic or meiotic cytokinesis should always be specified for manual annotation and for prokaryotic species use 'cytokinesis by binary fission ; GO:0043093'.

    From the comment it seems like the intent was to have a set of disjoint child terms for different kinds of cell division. But fission vs non-fission doesn't make sense for a prok/euk divide, as S. pombe is fission yeast, and there are bacteria that bud (e.g. Caulobacter).

    I believe that the definition of fission is based on the idea that there is equivalence in the inheritance of biological molecules between the two daughter cells, or at least the diffusible cytoplasmic parts. Even for E. coli, there is an old and new pole where cell wal material can be traced through multiple cell generations.

    So, cytokinesis by binary fission would be a sibling of

    • cytokinesis by budding
    • cytokinesis by schizogony (http://en.impact-malaria.com/web/malaria_training/strategies_schizogony)

    There might be a different axis to divide cytokinesis children based on the mechanism driving the constriction complex that does the actual division.

    • actin/microtubule-dependent cytokinesis
    • FtsZ-dependent cytokinesis
    • Cdv-dependent cytokinesis (http://www.pnas.org/content/105/48/18942.full.pdf)

    On top of that, plants don't do constriction at all (and I wouldn't be surprised if some prokaryote or protist did something more like what plants do).

     
  • David Hill

    David Hill - 2014-05-09

    Hi Jim,

    Ah, now I see what you are getting at. I think based on the definition of the current binary fission term, the best way to proceed would be to take the latter approach. I think I should change the name of the current binary fission term to 'Fts-dependent cytokinesis' and add the other two sibs you suggest. Then I will move the plant term, 'cytokinesis by cell plate formation', back as a sib of these because plants also have meiotic cytokinesis. Then I'll move the part_of children that are specific to the actin/tubulin processes under the new actin/microtubule term. Right now they are incorrectly placed because they are not part of all types cytokinesis.

    -David

     
  • Valerie Wood

    Valerie Wood - 2014-05-13

    Works for me.
    Val

     
  • David Hill

    David Hill - 2014-08-21

    Did the first bit of edits on this thread. I renamed the existing binary fission term to FtsZ-dependent cytokinesis and I created the new Cdv-dependent cytokinesis. I still need to create the actin/microtubule term and sort out all of the current children.\

    -D

     
  • David Hill

    David Hill - 2014-08-22

    Created the new cytoskeleton-dependent cytokinesis term and moved all of the appropriate children to it. Changed a few logical definitions to make them more specific to fit the new structure.

     
  • David Hill

    David Hill - 2014-08-22
    • status: open --> closed-fixed
     

Log in to post a comment.